Iris Bruchhaus
Overview
Explore the profile of Iris Bruchhaus including associated specialties, affiliations and a list of published articles.
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Articles
75
Citations
1646
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Recent Articles
1.
Allweier J, Bartels M, Torabi H, Tauler M, Metwally N, Roeder T, et al.
Mol Microbiol
. 2024 Dec;
122(6):948-967.
PMID: 39630601
Malaria remains a significant global health problem, mainly due to Plasmodium falciparum, which is responsible for most fatal infections. Infected red blood cells (iRBCs) evade spleen clearance by adhering to...
2.
Metwally N, Tauler M, Torabi H, Allweier J, Mohamed S, Bessemoulin M, et al.
iScience
. 2024 Nov;
27(11):111265.
PMID: 39569379
MicroRNAs (miRNAs) control 60% of genes expressed in the human body, but their role in malaria pathogenesis is incompletely understood. Here, we demonstrate cell type-specific alterations to the miRNA profiles...
3.
Anders J, Konig C, Lender C, Hellhund A, Nehls S, Shalabi I, et al.
PLoS Pathog
. 2023 Dec;
19(12):e1011745.
PMID: 38134215
Recently, two genes involved in amoebic liver abscess formation in a mouse model were identified by their differential expression of non-pathogenic (A1np) and pathogenic (B2p) clones of the Entamoeba histolytica...
4.
Wu Y, Leyk S, Torabi H, Hohn K, Honecker B, Tauler M, et al.
iScience
. 2023 Aug;
26(7):107119.
PMID: 37534175
, a human malaria parasite, develops in red blood cells (RBCs), which represent approximately 70% of all human blood cells. Additionally, RBC-derived extracellular vesicles (RBC-EVs) represent 7.3% of the total...
5.
Ma Y, He J, Sieber M, von Frieling J, Bruchhaus I, Baines J, et al.
Commun Biol
. 2023 Mar;
6(1):289.
PMID: 36934156
The close association between animals and their associated microbiota is usually beneficial for both partners. Here, we used a simple marine model invertebrate, the flatworm Macrostomum lignano, to characterize the...
6.
Bachmann A, Metwally N, Allweier J, Cronshagen J, Tauler M, Murk A, et al.
Microorganisms
. 2022 Dec;
10(12).
PMID: 36557610
infected erythrocytes (IEs) present erythrocyte membrane protein 1 proteins (EMP1s) on the cell surface, via which they cytoadhere to various endothelial cell receptors (ECRs) on the walls of human blood...
7.
Tahanzadeh N, Knop M, Seidler Y, Dirndorfer S, Lursen K, Bruchhaus I, et al.
Aging (Albany NY)
. 2022 Aug;
14(16):6427-6448.
PMID: 35980274
Food has a decisive influence on our health, to the extent where even lifespan can be directly affected by it. In the present work, we have examined the effects of...
8.
Rehn T, Lubiana P, Nguyen T, Pansegrau E, Schmitt M, Roth L, et al.
Microorganisms
. 2022 Jun;
10(6).
PMID: 35744701
-infected erythrocytes (IEs) adhere to endothelial cell receptors (ECRs) of blood vessels mainly via EMP1 proteins to escape elimination via the spleen. Evidence suggests that -infected reticulocytes (IRs) also bind...
9.
Verner Z, Zarsky V, Le T, Narayanasamy R, Rada P, Rozbesky D, et al.
PLoS Pathog
. 2021 Nov;
17(11):e1010041.
PMID: 34780573
Entamoeba histolytica is believed to be devoid of peroxisomes, like most anaerobic protists. In this work, we provided the first evidence that peroxisomes are present in E. histolytica, although only...
10.
Groneberg M, Hoenow S, Marggraff C, Fehling H, Metwally N, Hansen C, et al.
J Hepatol
. 2021 Oct;
76(1):160-173.
PMID: 34599999
Background & Aims: An invasive form of intestinal Entamoeba (E.) histolytica infection, which causes amoebic liver abscess, is more common in men than in women. Immunopathological mechanisms are responsible for...