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Stepan Koudelka

Explore the profile of Stepan Koudelka including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 20
Citations 294
Followers 0
Related Specialties
Pharmacology
Pharmacy
Chemistry
Top 10 Co-Authors
Jaroslav Turanek
Josef Masek
Eliska Bartheldyova
Andrew D Miller
Milan Raska
Jana Plockova
Pavel Kulich
Robert Lukac
Pavlina Turanek Knotigova
Miroslav Ledvina
Published In
J Control Release
J Pharm Sci
Toxicol Appl Pharmacol
Apoptosis
PLoS One
Affiliations
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Recent Articles
1.
Open, High-Resolution EI+ Spectral Library of Anthropogenic Compounds
Price E, Palat J, Coufalikova K, Kukucka P, Codling G, Vitale C, et al.
Front Public Health . 2021 Mar; 9:622558. PMID: 33768085
To address the lack of high-resolution electron ionisation mass spectral libraries (HR-[EI+]-MS) for environmental chemicals, a retention-indexed HR-[EI+]-MS library has been constructed following analysis of authentic compounds via GC-Orbitrap MS....
2.
Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo
Effenberg R, Knotigova P, Zyka D, celechovska H, Masek J, Bartheldyova E, et al.
J Med Chem . 2017 Aug; 60(18):7745-7763. PMID: 28829599
Fatty acyl analogues of muramyldipeptide (MDP) (abbreviated N-L18 norAbuGMDP, N-B30 norAbuGMDP, norAbuMDP-Lys(L18), norAbuMDP-Lys(B30), norAbuGMDP-Lys(L18), norAbuGMDP-Lys(B30), B30 norAbuMDP, L18 norAbuMDP) are designed and synthesized comprising the normuramyl-l-α-aminobutanoyl (norAbu) structural moiety. All...
3.
Multi-layered nanofibrous mucoadhesive films for buccal and sublingual administration of drug-delivery and vaccination nanoparticles - important step towards effective mucosal vaccines
Masek J, Lubasova D, Lukac R, Turanek-Knotigova P, Kulich P, Plockova J, et al.
J Control Release . 2016 Jul; 249:183-195. PMID: 27469472
Nanofibre-based mucoadhesive films were invented for oromucosal administration of nanocarriers used for delivery of drugs and vaccines. The mucoadhesive film consists of an electrospun nanofibrous reservoir layer, a mucoadhesive film...
4.
Liposomal nanocarriers for plasminogen activators
Koudelka S, Mikulik R, Masek J, Raska M, Knotigova P, Miller A, et al.
J Control Release . 2016 Feb; 227:45-57. PMID: 26876783
Several plasminogen activators (PAs) have been found effective in treating different thromboembolic diseases. However, administration of conventional thrombolytic therapy is limited by a low efficacy of present formulations of PAs....
5.
Antiviral activities of 2,6-diaminopurine-based acyclic nucleoside phosphonates against herpesviruses: In vitro study results with pseudorabies virus (PrV, SuHV-1)
Zouharova D, Lipenska I, Fojtikova M, Kulich P, Neca J, Slany M, et al.
Vet Microbiol . 2016 Feb; 184:84-93. PMID: 26854349
Pseudorabies virus (PrV), a causative agent of Aujeszky's disease, is deadly to most mammals with the exception of higher primates and men. This disease causes serious economic loses among farm...
6.
The Position of His-Tag in Recombinant OspC and Application of Various Adjuvants Affects the Intensity and Quality of Specific Antibody Response after Immunization of Experimental Mice
Krupka M, Masek J, Barkocziova L, Knotigova P, Kulich P, Plockova J, et al.
PLoS One . 2016 Feb; 11(2):e0148497. PMID: 26848589
Lyme disease, Borrelia burgdorferi-caused infection, if not recognized and appropriately treated by antibiotics, may lead to chronic complications, thus stressing the need for protective vaccine development. The immune protection is...
7.
Liposomal delivery systems for anti-cancer analogues of vitamin E
Koudelka S, Knotigova P, Masek J, Prochazka L, Lukac R, Miller A, et al.
J Control Release . 2015 Apr; 207:59-69. PMID: 25861728
Pro-apoptotic analogues of vitamin E (VE) exert selective anti-cancer effect on various animal cancer models. Neither suitable formulation of α-tocopheryl succinate (α-TOS), representative semi-synthetic VE analogue ester, nor suitable formulations...
8.
Molecular adjuvants based on nonpyrogenic lipophilic derivatives of norAbuMDP/GMDP formulated in nanoliposomes: stimulation of innate and adaptive immunity
Knotigova P, Zyka D, Masek J, Kovalova A, Krupka M, Bartheldyova E, et al.
Pharm Res . 2015 Jan; 32(4):1186-99. PMID: 25630814
Purpose: The aim of this work was to demonstrate an immunostimulatory and adjuvant effect of new apyrogenic lipophilic derivatives of norAbuMDP and norAbuGMDP formulated in nanoliposomes. Methods: Nanoliposomes and metallochelating...
9.
Specific contrast ultrasound using sterically stabilized microbubbles for early diagnosis of thromboembolic disease in a rabbit model
Vlasin M, Lukac R, Kauerova Z, Kohout P, Masek J, Bartheldyova E, et al.
Can J Vet Res . 2014 Apr; 78(2):133-9. PMID: 24688175
Specific contrast ultrasound is widely applied in diagnostic procedures on humans but remains underused in veterinary medicine. The objective of this study was to evaluate the use of microbubble-based contrast...
10.
Mitochondrial targeting overcomes ABCA1-dependent resistance of lung carcinoma to α-tocopheryl succinate
Prochazka L, Koudelka S, Dong L, Stursa J, Goodwin J, Neca J, et al.
Apoptosis . 2013 Jan; 18(3):286-99. PMID: 23299931
α-Tocopheryl succinate (α-TOS) is a promising anti-cancer agent due to its selectivity for cancer cells. It is important to understand whether long-term exposure of tumour cells to the agent will...