Robert Lukac
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Explore the profile of Robert Lukac including associated specialties, affiliations and a list of published articles.
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9
Citations
92
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Recent Articles
1.
Effenberg R, Knotigova P, Zyka D, celechovska H, Masek J, Bartheldyova E, et al.
J Med Chem
. 2017 Aug;
60(18):7745-7763.
PMID: 28829599
Fatty acyl analogues of muramyldipeptide (MDP) (abbreviated N-L18 norAbuGMDP, N-B30 norAbuGMDP, norAbuMDP-Lys(L18), norAbuMDP-Lys(B30), norAbuGMDP-Lys(L18), norAbuGMDP-Lys(B30), B30 norAbuMDP, L18 norAbuMDP) are designed and synthesized comprising the normuramyl-l-α-aminobutanoyl (norAbu) structural moiety. All...
2.
Masek J, Lubasova D, Lukac R, Turanek-Knotigova P, Kulich P, Plockova J, et al.
J Control Release
. 2016 Jul;
249:183-195.
PMID: 27469472
Nanofibre-based mucoadhesive films were invented for oromucosal administration of nanocarriers used for delivery of drugs and vaccines. The mucoadhesive film consists of an electrospun nanofibrous reservoir layer, a mucoadhesive film...
3.
Krupka M, Masek J, Barkocziova L, Knotigova P, Kulich P, Plockova J, et al.
PLoS One
. 2016 Feb;
11(2):e0148497.
PMID: 26848589
Lyme disease, Borrelia burgdorferi-caused infection, if not recognized and appropriately treated by antibiotics, may lead to chronic complications, thus stressing the need for protective vaccine development. The immune protection is...
4.
Koudelka S, Knotigova P, Masek J, Prochazka L, Lukac R, Miller A, et al.
J Control Release
. 2015 Apr;
207:59-69.
PMID: 25861728
Pro-apoptotic analogues of vitamin E (VE) exert selective anti-cancer effect on various animal cancer models. Neither suitable formulation of α-tocopheryl succinate (α-TOS), representative semi-synthetic VE analogue ester, nor suitable formulations...
5.
Knotigova P, Zyka D, Masek J, Kovalova A, Krupka M, Bartheldyova E, et al.
Pharm Res
. 2015 Jan;
32(4):1186-99.
PMID: 25630814
Purpose: The aim of this work was to demonstrate an immunostimulatory and adjuvant effect of new apyrogenic lipophilic derivatives of norAbuMDP and norAbuGMDP formulated in nanoliposomes. Methods: Nanoliposomes and metallochelating...
6.
Vyslouzil J, Dolezel P, Kejdusova M, Maskova E, Masek J, Lukac R, et al.
Acta Pharm
. 2014 Dec;
64(4):403-17.
PMID: 25531782
The main objective of this study was to evaluate the influence of the formulation and process parameters on PLGA microparticles containing a practically insoluble model drug (ibuprofen) prepared by the...
7.
Vlasin M, Lukac R, Kauerova Z, Kohout P, Masek J, Bartheldyova E, et al.
Can J Vet Res
. 2014 Apr;
78(2):133-9.
PMID: 24688175
Specific contrast ultrasound is widely applied in diagnostic procedures on humans but remains underused in veterinary medicine. The objective of this study was to evaluate the use of microbubble-based contrast...
8.
Kauerova Z, Lukac R, Kohout P, Masek J, Koudelka S, Plockova J, et al.
Int J Pharm
. 2012 Dec;
441(1-2):92-8.
PMID: 23266760
A device for continuous infusion of microbubbles (MBs) 'Infucon' has been designed, constructed and tested on rabbits. The device prevents MBs from flotation and accumulation in the layer directly below...
9.
Lukac R, Kauerova Z, Masek J, Bartheldyova E, Kulich P, Koudelka S, et al.
Langmuir
. 2011 Mar;
27(8):4829-37.
PMID: 21417344
The histidine-metallochelating lipid complex is one of the smallest high affinity binding units used as tools for rapid noncovalent binding of histidine tagged molecules, especially recombinant proteins. The advantage of...