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» Authors » Eliska Bartheldyova

Eliska Bartheldyova

Explore the profile of Eliska Bartheldyova including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 20
Citations 176
Followers 0
Related Specialties
Pharmacology
Biochemistry
Chemistry
Top 10 Co-Authors
Jaroslav Turanek
Josef Masek
Pavel Kulich
Milan Raska
Stepan Koudelka
Andrew D Miller
Pavlina Turanek Knotigova
Frantisek Hubatka
Miroslav Ledvina
Jana Plockova
Published In
J Control Release
Pharmaceutics
J Pharm Sci
Langmuir
PLoS One
Affiliations
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Recent Articles
1.
Long circulating liposomal platform utilizing hydrophilic polymer-based surface modification: preparation, characterisation, and biological evaluation
Turanek J, Kosztyu P, Knotigova P, Bartheldyova E, Hubatka F, Odehnalova N, et al.
Int J Pharm . 2024 Jul; 661:124465. PMID: 39004290
Liposomes are one of the most important drug delivery vectors, nowadays used in clinics. In general, polyethylene glycol (PEG) is used to ensure the stealth properties of the liposomes. Here,...
2.
Hexahelicene DNA-binding: Minor groove selectivity, semi-intercalation and chiral recognition
Vacek J, Zatloukalova M, Bartheldyova E, reha D, Minofar B, Bednarova K, et al.
Int J Biol Macromol . 2023 Jul; 250:125905. PMID: 37487990
In this contribution, we focused on a fundamental study targeting the interaction of water-soluble [6]helicene derivative 1 (1-butyl-3-(2-methyl[6]helicenyl)-imidazolium bromide) with double-stranded (ds) DNA. A synthetic 30-base pair duplex, plasmid, chromosomal...
3.
Thrombus Imaging Using 3D Printed Middle Cerebral Artery Model and Preclinical Imaging Techniques: Application to Thrombus Targeting and Thrombolytic Studies
Viteckova Wunschova A, Novobilsky A, Hlozkova J, Scheer P, Petrokova H, Jirik R, et al.
Pharmaceutics . 2020 Dec; 12(12). PMID: 33322710
Diseases with the highest burden for society such as stroke, myocardial infarction, pulmonary embolism, and others are due to blood clots. Preclinical and clinical techniques to study blood clots are...
4.
Preparation of nanoliposomes by microfluidic mixing in herring-bone channel and the role of membrane fluidity in liposomes formation
Kotoucek J, Hubatka F, Masek J, Kulich P, Velinska K, Bezdekova J, et al.
Sci Rep . 2020 Mar; 10(1):5595. PMID: 32221374
Introduction of microfluidic mixing technique opens a new door for preparation of the liposomes and lipid-based nanoparticles by on-chip technologies that are applicable in a laboratory and industrial scale. This...
5.
Targeting Human Thrombus by Liposomes Modified with Anti-Fibrin Protein Binders
Petrokova H, Masek J, Kuchar M, Viteckova Wunschova A, Stikarova J, Bartheldyova E, et al.
Pharmaceutics . 2019 Dec; 11(12). PMID: 31810280
Development of tools for direct thrombus imaging represents a key step for diagnosis and treatment of stroke. Nanoliposomal carriers of contrast agents and thrombolytics can be functionalized to target blood...
6.
Application of Advanced Microscopic Methods to Study the Interaction of Carboxylated Fluorescent Nanodiamonds with Membrane Structures in THP-1 Cells: Activation of Inflammasome NLRP3 as the Result of Lysosome Destabilization
Knotigova P, Masek J, Hubatka F, Kotoucek J, Kulich P, Simeckova P, et al.
Mol Pharm . 2019 Jun; 16(8):3441-3451. PMID: 31184896
Nanodiamonds (ND), especially fluorescent NDs, represent potentially applicable drug and probe carriers for in vitro/in vivo applications. The main purpose of this study was to relate physical-chemical properties of carboxylated...
7.
N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells
Bartheldyova E, Knotigova P, Zachova K, Masek J, Kulich P, Effenberg R, et al.
Carbohydr Polym . 2019 Jan; 207:521-532. PMID: 30600036
New synthetic aminooxy lipid was designed and synthesized as a building block for the formulation of functionalised nanoliposomes (presenting onto the outer surface of aminooxy groups) by microfluidic mixing. Orthogonal...
8.
Hyaluronic Acid Surface Modified Liposomes Prepared via Orthogonal Aminoxy Coupling: Synthesis of Nontoxic Aminoxylipids Based on Symmetrically α-Branched Fatty Acids, Preparation of Liposomes by Microfluidic Mixing, and Targeting to Cancer Cells...
Bartheldyova E, Effenberg R, Masek J, Prochazka L, Knotigova P, Kulich P, et al.
Bioconjug Chem . 2018 Jun; 29(7):2343-2356. PMID: 29898364
New synthetic aminoxy lipids are designed and synthesized as building blocks for the formulation of functionalized nanoliposomes by microfluidization using a NanoAssemblr. Orthogonal binding of hyaluronic acid onto the outer...
9.
Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo
Effenberg R, Knotigova P, Zyka D, celechovska H, Masek J, Bartheldyova E, et al.
J Med Chem . 2017 Aug; 60(18):7745-7763. PMID: 28829599
Fatty acyl analogues of muramyldipeptide (MDP) (abbreviated N-L18 norAbuGMDP, N-B30 norAbuGMDP, norAbuMDP-Lys(L18), norAbuMDP-Lys(B30), norAbuGMDP-Lys(L18), norAbuGMDP-Lys(B30), B30 norAbuMDP, L18 norAbuMDP) are designed and synthesized comprising the normuramyl-l-α-aminobutanoyl (norAbu) structural moiety. All...
10.
Multi-layered nanofibrous mucoadhesive films for buccal and sublingual administration of drug-delivery and vaccination nanoparticles - important step towards effective mucosal vaccines
Masek J, Lubasova D, Lukac R, Turanek-Knotigova P, Kulich P, Plockova J, et al.
J Control Release . 2016 Jul; 249:183-195. PMID: 27469472
Nanofibre-based mucoadhesive films were invented for oromucosal administration of nanocarriers used for delivery of drugs and vaccines. The mucoadhesive film consists of an electrospun nanofibrous reservoir layer, a mucoadhesive film...