Stefen A Boehme
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Explore the profile of Stefen A Boehme including associated specialties, affiliations and a list of published articles.
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12
Citations
226
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Recent Articles
1.
Garcia D, Pierre A, Quirino L, Acharya G, Vasudevan A, Pei Y, et al.
Mol Ther
. 2024 Nov;
33(1):90-103.
PMID: 39563033
Lipoprotein(a), or Lp(a), is encoded by the LPA gene and is a causal genetic risk factor for cardiovascular disease. Individuals with high Lp(a) are at risk for cardiovascular morbidity and...
2.
Jones I, Espindola M, Narayanan R, Coelho A, Habiel D, Boehme S, et al.
Sci Rep
. 2019 Dec;
9(1):19796.
PMID: 31875033
Idiopathic Pulmonary Fibrosis (IPF) is a disease with a devastating prognosis characterized by unrelenting lung scarring. Aberrant activation of lung fibroblasts is a key feature of this disease, yet the...
3.
Boehme S, Franz-Bacon K, Ludka J, DiTirro D, Ly T, Bacon K
PLoS One
. 2016 Dec;
11(12):e0167169.
PMID: 27935962
Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung inflammation resulting in a progressive decline in lung function whose principle cause is cigarette smoke. MAP3K19 is...
4.
Boehme S, Franz-Bacon K, DiTirro D, Ly T, Bacon K
PLoS One
. 2016 May;
11(5):e0154874.
PMID: 27144281
Idiopathic pulmonary fibrosis (IPF) is a progressive, debilitating disease for which two medications, pirfenidone and nintedanib, have only recently been approved for treatment. The cytokine TGF-β has been shown to...
5.
Boehme S, Franz-Bacon K, Chen E, Ly T, Kawakami Y, Bacon K
Int Immunol
. 2009 Apr;
21(6):621-32.
PMID: 19346259
Mast cells are bone marrow-derived effector cells that can initiate inflammatory responses to infectious organisms or allergens by releasing a multitude of pro-inflammatory factors including prostaglandin (PG) D(2). We demonstrate...
6.
Boehme S, Chen E, Franz-Bacon K, Sasik R, Sprague L, Ly T, et al.
Int Immunol
. 2008 Dec;
21(1):1-17.
PMID: 19066315
Prostaglandin D(2) (PGD(2)) and its receptor chemoattractant receptor homologous molecule expressed on T(h)2 cells (CRTH2) have been implicated in the pathogenesis of numerous allergic diseases. We investigated the role of...
7.
Boehme S, Franz-Bacon K, Chen E, Sasik R, Sprague L, Ly T, et al.
Int Immunol
. 2008 Dec;
21(1):81-93.
PMID: 19066314
A FITC-induced allergic contact hypersensitivity model was used to investigate the role that the prostaglandin D(2) receptor-chemoattractant receptor-homologous molecule expressed on T(h)2 cells (CRTH2) plays in modulating cutaneous inflammation. Our...
8.
Lukacs N, Berlin A, Franz-Bacon K, Sasik R, Sprague L, Ly T, et al.
Am J Physiol Lung Cell Mol Physiol
. 2008 Sep;
295(5):L767-79.
PMID: 18757520
Prostaglandin D(2), the ligand for the G protein-coupled receptors DP1 and CRTH2, has been implicated in the pathogenesis of the allergic response in diseases such as asthma, rhinitis, and atopic...
9.
Boehme S, Lio F, Sikora L, Pandit T, Lavrador K, Rao S, et al.
J Immunol
. 2004 Sep;
173(6):3599-603.
PMID: 15356103
Elevated levels of serotonin (5-hydroxytryptamine, 5-HT) are observed in the serum of asthmatics. Herein, we demonstrate that 5-HT functions independently as an eosinophil chemoattractant that acts additively with eotaxin. 5-HT2A...
10.
Davis C, Chen S, Boehme S, Bacon K, Harrison J
Methods
. 2003 May;
29(4):326-34.
PMID: 12725799
Chemokine receptors belong to the superfamily of seven-transmembrane-spanning, G-protein-coupled receptors, and their expression by central nervous system cells is clearly documented. As this gene family has become the target of...