Stefano Espinoza
Overview
Explore the profile of Stefano Espinoza including associated specialties, affiliations and a list of published articles.
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46
Citations
1051
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Recent Articles
1.
Di Leva F, Arnoldi M, Santarelli S, Massonot M, Lemee M, Bon C, et al.
Mol Ther
. 2025 Jan;
33(3):1180-1196.
PMID: 39741407
Loss-of-function mutations in the chromodomain helicase DNA-binding 8 (CHD8) gene are strongly associated with autism spectrum disorders (ASDs). Indeed, the reduction of CHD8 causes transcriptional, epigenetic, and cellular phenotypic changes...
2.
Scarano N, Espinoza S, Brullo C, Cichero E
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125796
G-protein-coupled receptors (GPCRs) represent a family of druggable targets when treating several diseases and continue to be a leading part of the drug discovery process. Trace amine-associated receptors (TAARs) are...
3.
Cichero E, Francesconi V, Casini B, Casale M, Kanov E, Gerasimov A, et al.
Pharmaceuticals (Basel)
. 2023 Nov;
16(11).
PMID: 38004497
Trace amine-associated receptor 1 (TAAR1) is an attractive target for the design of innovative drugs to be applied in diverse pharmacological settings. Due to a non-negligible structural similarity with endogenous...
4.
Nicoli A, Weber V, Bon C, Steuer A, Gustincich S, Gainetdinov R, et al.
J Chem Inf Model
. 2023 Oct;
63(21):6667-6680.
PMID: 37847527
Trace amine-associated receptors (TAARs) were discovered in 2001 as new members of class A G protein-coupled receptors (GPCRs). With the only exception of TAAR1, TAAR members (TAAR2-9, also known as...
5.
Pierattini B, DAgostino S, Bon C, Peruzzo O, Alendar A, Codino A, et al.
Mol Ther Nucleic Acids
. 2023 May;
32:402-414.
PMID: 37187707
SINEUPs are natural and synthetic antisense long non-coding RNAs (lncRNAs) selectively enhancing target mRNAs translation by increasing their association with polysomes. This activity requires two RNA domains: an embedded inverted...
6.
Santulli C, Bon C, De Cecco E, Codrich M, Narkiewicz J, Parisse P, et al.
Cell Death Dis
. 2022 Dec;
13(12):1048.
PMID: 36526614
Parkinson's disease (PD) presents the selective loss of A9 dopaminergic (DA) neurons of Substantia Nigra pars compacta (SNpc) and the presence of intracellular aggregates called Lewy bodies. α-synuclein (α-syn) species...
7.
Maggi S, Bon C, Gustincich S, Tucci V, Gainetdinov R, Espinoza S
Sci Rep
. 2022 Aug;
12(1):14708.
PMID: 36038766
Trace amine-associated receptors (TAARs) are a family of G protein-coupled receptors present in mammals in the brain and several peripheral organs. Apart from its olfactory role, TAAR5 is expressed in...
8.
Favero F, Barberis E, Gagliardi M, Espinoza S, Contu L, Gustincich S, et al.
PLoS One
. 2022 Aug;
17(8):e0273036.
PMID: 36001607
The key role played by host-microbiota interactions on human health, disease onset and progression, and on host response to treatments has increasingly emerged in the latest decades. Indeed, dysbiosis has...
9.
Leo D, Targa G, Espinoza S, Villers A, Gainetdinov R, Ris L
Int J Mol Sci
. 2022 Jul;
23(14).
PMID: 35887159
Worldwide, approximately 27 million people are affected by Alzheimer's disease (AD). AD pathophysiology is believed to be caused by the deposition of the β-amyloid peptide (Aβ). Aβ can reduce long-term...
10.
Bon C, Chern T, Cichero E, OBrien T, Gustincich S, Gainetdinov R, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328548
Trace amine-associated receptor 5 (TAAR5) is a G protein-coupled receptor that belongs to the TAARs family (TAAR1-TAAR9). TAAR5 is expressed in the olfactory epithelium and is responsible for sensing 3-methylamine...