Stefano Cairo
Overview
Explore the profile of Stefano Cairo including associated specialties, affiliations and a list of published articles.
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77
Citations
2236
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Recent Articles
1.
Demir S, Hotes A, Schmid T, Cairo S, Indersie E, Pisano C, et al.
J Exp Clin Cancer Res
. 2024 Nov;
43(1):299.
PMID: 39529166
Background: Patients with metastatic hepatoblastoma are treated with severely toxic first-line chemotherapies in combination with surgery. Yet, inadequate response of lung metastases to neo-adjuvant chemotherapy still compromises patient outcomes making...
2.
Cavazzoni A, Salamon I, Fumarola C, Gallerani G, Laprovitera N, Gelsomino F, et al.
Mol Ther
. 2024 Jul;
32(10):3650-3668.
PMID: 39033323
Patients with cancer of unknown primary (CUP) carry the double burden of an aggressive disease and reduced access to therapies. Experimental models are pivotal for CUP biology investigation and drug...
3.
Demir S, Razizadeh N, Indersie E, Branchereau S, Cairo S, Kappler R
Hepatol Commun
. 2024 Jan;
8(2).
PMID: 38285887
Background: As the variable clinical outcome of patients with hepatoblastoma (HB) cannot be explained by genetics alone, the identification of drugs with the potential to effectively reverse epigenetic alterations is...
4.
Cornet M, Brulle-Soumare L, Bisio V, Deas O, Mussini C, Guettier C, et al.
Pediatr Res
. 2024 Jan;
96(3):668-677.
PMID: 38263451
Background: Twenty percent of children with hepatoblastoma (HB) have lung metastasis at diagnosis. Treatment protocols recommend surgical removal of chemotherapy-refractory lung nodules, however no chronological order is established. As hepatectomy...
5.
Glaser K, Schepers E, Zwolshen H, Lake C, Timchenko N, Karns R, et al.
Pediatr Blood Cancer
. 2023 Nov;
71(2):e30774.
PMID: 37990130
Background: Enhancer of zeste homolog 2 (EZH2) catalyzes the trimethylation of histone H3 at lysine 27 via the polycomb recessive complex 2 (PRC2) and plays a time-specific role in normal...
6.
Failli M, Demir S, Del Rio-Alvarez A, Carrillo-Reixach J, Royo L, Domingo-Sabat M, et al.
Hepatology
. 2023 Sep;
80(1):55-68.
PMID: 37729391
Background And Aims: Hepatoblastoma (HB) is the predominant form of pediatric liver cancer, though it remains exceptionally rare. While treatment outcomes for children with HB have improved, patients with advanced...
7.
Marques Da Costa M, Zaidi S, Scoazec J, Droit R, Lim W, Marchais A, et al.
Commun Biol
. 2023 Sep;
6(1):949.
PMID: 37723198
Pediatric patients with recurrent and refractory cancers are in most need for new treatments. This study developed patient-derived-xenograft (PDX) models within the European MAPPYACTS cancer precision medicine trial (NCT02613962). To...
8.
Fang J, Singh S, Cheng C, Natarajan S, Sheppard H, Abu-Zaid A, et al.
Nat Commun
. 2023 Jul;
14(1):4003.
PMID: 37414763
A lack of relevant genetic models and cell lines hampers our understanding of hepatoblastoma pathogenesis and the development of new therapies for this neoplasm. Here, we report an improved MYC-driven...
9.
Nousiainen R, Eloranta K, Isoaho N, Cairo S, Wilson D, Heikinheimo M, et al.
Front Genet
. 2023 Jun;
14:1170940.
PMID: 37377594
Hepatoblastoma (HB) is the most common malignant liver tumor among children. To gain insight into the pathobiology of HB, we performed RNA sequence analysis on 5 patient-derived xenograft lines (HB-243,...
10.
Claveria-Cabello A, Herranz J, Latasa M, Arechederra M, Uriarte I, Pineda-Lucena A, et al.
J Hepatol
. 2023 Jun;
79(4):989-1005.
PMID: 37302584
Background & Aims: Hepatoblastoma (HB) is the most frequent childhood liver cancer. Patients with aggressive tumors have limited therapeutic options; therefore, a better understanding of HB pathogenesis is needed to...