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Stefanie Klima

Explore the profile of Stefanie Klima including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 233
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Recent Articles
11.
Delp J, Gutbier S, Klima S, Hoelting L, Pinto-Gil K, Hsieh J, et al.
ALTEX . 2018 Feb; 35(2):235-253. PMID: 29423527
The (developmental) neurotoxicity hazard is still unknown for most chemicals. Establishing a test battery covering most of the relevant adverse outcome pathways may close this gap, without requiring a huge...
12.
Hoelting L, Klima S, Karreman C, Grinberg M, Meisig J, Henry M, et al.
Stem Cells Transl Med . 2016 Mar; 5(4):476-87. PMID: 26933043
Unlabelled: Safety sciences and the identification of chemical hazards have been seen as one of the most immediate practical applications of human pluripotent stem cell technology. Protocols for the generation...
13.
Shinde V, Klima S, Sureshkumar P, Meganathan K, Jagtap S, Rempel E, et al.
J Vis Exp . 2015 Jul; (100):e52333. PMID: 26132533
Efficient protocols to differentiate human pluripotent stem cells to various tissues in combination with -omics technologies opened up new horizons for in vitro toxicity testing of potential drugs. To provide...
14.
Balmer N, Klima S, Rempel E, Ivanova V, Kolde R, Weng M, et al.
Arch Toxicol . 2014 Jun; 88(7):1451-68. PMID: 24935251
The superordinate principles governing the transcriptome response of differentiating cells exposed to drugs are still unclear. Often, it is assumed that toxicogenomics data reflect the immediate mode of action (MoA)...