Stefan M Muehlbauer
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Explore the profile of Stefan M Muehlbauer including associated specialties, affiliations and a list of published articles.
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10
Citations
230
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Recent Articles
1.
Chen L, Burdowski J, Marfatia R, Weber J, Gliganic K, Diaz N, et al.
Clin Cardiol
. 2020 Dec;
43(12):1547-1554.
PMID: 33280140
Background: Cardiac injury is common in COVID-19 patients and is associated with increased mortality. However, it remains unclear if reduced cardiac function is associated with cardiac injury, and additionally if...
2.
Brojatsch J, Lima Jr H, Palliser D, Jacobson L, Muehlbauer S, Furtado R, et al.
Cell Cycle
. 2015 Apr;
14(7):964-72.
PMID: 25830414
Necrotic cell death triggers a range of biological responses including a strong adaptive immune response, yet we know little about the cellular pathways that control necrotic cell death. Inhibitor studies...
3.
Brojatsch J, Lima H, Kar A, Jacobson L, Muehlbauer S, Chandran K, et al.
PLoS One
. 2014 Jun;
9(6):e95032.
PMID: 24893007
Recent studies have linked necrotic cell death and proteolysis of inflammatory proteins to the adaptive immune response mediated by the lysosome-destabilizing adjuvants, alum and Leu-Leu-OMe (LLOMe). However, the mechanism by...
4.
Muehlbauer S, Lima Jr H, Goldman D, Jacobson L, Rivera J, Goldberg M, et al.
Am J Pathol
. 2010 Jul;
177(2):735-43.
PMID: 20595632
NOD-like receptors (NLRs) and caspase-1 are critical components of innate immunity, yet their over-activation has been linked to a long list of microbial and inflammatory diseases, including anthrax. The Bacillus...
5.
Dodatko T, Akoachere M, Muehlbauer S, Helfrich F, Howerton A, Ross C, et al.
PLoS One
. 2009 Jul;
4(7):e6398.
PMID: 19636427
Background: The first step of the bacterial lifecycle is the germination of bacterial spores into their vegetative form, which requires the presence of specific nutrients. In contrast to closely related...
6.
Diaz-Griffero F, Taube R, Muehlbauer S, Brojatsch J
Biochem Biophys Res Commun
. 2008 Feb;
368(3):463-9.
PMID: 18241668
Previous efforts to develop a mouse model for HIV/AIDS have been impaired by multiple blocks to HIV replication, including barriers to viral entry, proviral transcription, and assembly. Expression of human...
7.
Squires R, Muehlbauer S, Brojatsch J
J Biol Chem
. 2007 Sep;
282(47):34260-7.
PMID: 17878154
Activation of caspase-1 through the inflammasome protein Nalp1b controls anthrax lethal toxin (LT)-induced necrosis in murine macrophages. In this study we analyzed physiological changes controlled by caspase-1 in LT-treated murine...
8.
Muehlbauer S, Evering T, Bonuccelli G, Squires R, Ashton A, Porcelli S, et al.
Cell Cycle
. 2007 Mar;
6(6):758-66.
PMID: 17374996
Murine macrophages have been classified as either susceptible or nonsusceptible to killing by anthrax lethal toxin (LT) depending upon genetic background. While considered resistant to LT killing, we found that...
9.
Alileche A, Squires R, Muehlbauer S, Lisanti M, Brojatsch J
Cell Cycle
. 2005 Dec;
5(1):100-6.
PMID: 16357526
Numerous early events in anthrax lethal toxin (LT)-mediated cell killing have been described, including uptake of LT and MAPKK cleavage. However, critical downstream events in LT killing remain to be...
10.
Alileche A, Serfass E, Muehlbauer S, Porcelli S, Brojatsch J
PLoS Pathog
. 2005 Oct;
1(2):e19.
PMID: 16254597
Many pathogens have acquired strategies to combat the immune response. Bacillus anthracis interferes with host defenses by releasing anthrax lethal toxin (LT), which inactivates mitogen-activated protein kinase pathways, rendering dendritic...