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Heriberto Lima Jr

Explore the profile of Heriberto Lima Jr including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 513
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Recent Articles
1.
Brojatsch J, Lima Jr H, Palliser D, Jacobson L, Muehlbauer S, Furtado R, et al.
Cell Cycle . 2015 Apr; 14(7):964-72. PMID: 25830414
Necrotic cell death triggers a range of biological responses including a strong adaptive immune response, yet we know little about the cellular pathways that control necrotic cell death. Inhibitor studies...
2.
Lima Jr H, Jacobson L, Goldberg M, Chandran K, Diaz-Griffero F, Lisanti M, et al.
Cell Cycle . 2013 May; 12(12):1868-78. PMID: 23708522
The Nod-like receptor, Nlrp3, has been linked to inflammatory diseases and adjuvant-mediated immune responses. A wide array of structurally diverse agents does not interact directly with Nlrp3, but is thought...
3.
Jacobson L, Lima Jr H, Goldberg M, Gocheva V, Tsiperson V, Sutterwala F, et al.
J Biol Chem . 2013 Jan; 288(11):7481-7491. PMID: 23297415
Immunologic adjuvants are critical components of vaccines, but it remains unclear how prototypical adjuvants enhance the adaptive immune response. Recent studies have shown that necrotic cells could trigger an immune...
4.
Muehlbauer S, Lima Jr H, Goldman D, Jacobson L, Rivera J, Goldberg M, et al.
Am J Pathol . 2010 Jul; 177(2):735-43. PMID: 20595632
NOD-like receptors (NLRs) and caspase-1 are critical components of innate immunity, yet their over-activation has been linked to a long list of microbial and inflammatory diseases, including anthrax. The Bacillus...
5.
Wehkamp J, Salzman N, Porter E, Nuding S, Weichenthal M, Petras R, et al.
Proc Natl Acad Sci U S A . 2005 Dec; 102(50):18129-34. PMID: 16330776
The pathogenesis of Crohn's disease (CD), an idiopathic inflammatory bowel disease, is attributed, in part, to intestinal bacteria that may initiate and perpetuate mucosal inflammation in genetically susceptible individuals. Paneth...