Stefan J Kempf
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Explore the profile of Stefan J Kempf including associated specialties, affiliations and a list of published articles.
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24
Citations
437
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Recent Articles
11.
Kempf S, Janik D, Barjaktarovic Z, Braga-Tanaka 3rd I, Tanaka S, Neff F, et al.
Oncotarget
. 2016 Oct;
7(44):71817-71832.
PMID: 27708245
Accruing data indicate that radiation-induced consequences resemble pathologies of neurodegenerative diseases such as Alzheimer´s. The aim of this study was to elucidate the effect on hippocampus of chronic low-dose-rate radiation...
12.
Barjaktarovic Z, Merl-Pham J, Azimzadeh O, Kempf S, Raj K, Atkinson M, et al.
Int J Radiat Biol
. 2016 Sep;
93(2):156-164.
PMID: 27653672
Purpose: Ionizing radiation induces cardiovascular disease, the endothelium being the main target. The exact mechanism of the damage is unclear but the involvement of multiple signaling pathways is probable. Reversible...
13.
Karapiperis C, Kempf S, Quintens R, Azimzadeh O, Vidal V, Pazzaglia S, et al.
BMC Bioinformatics
. 2016 May;
17(1):212.
PMID: 27170263
Background: The underlying molecular processes representing stress responses to low-dose ionising radiation (LDIR) in mammals are just beginning to be understood. In particular, LDIR effects on the brain and their...
14.
Kempf S, Metaxas A, Ibanez-Vea M, Darvesh S, Finsen B, Larsen M
Oncotarget
. 2016 May;
7(23):33627-48.
PMID: 27144524
The aim of this study was to elucidate the molecular signature of Alzheimer's disease-associated amyloid pathology.We used the double APPswe/PS1ΔE9 mouse, a widely used model of cerebral amyloidosis, to compare...
15.
Casciati A, Dobos K, Antonelli F, Benedek A, Kempf S, Belles M, et al.
Oncotarget
. 2016 Apr;
7(19):28040-58.
PMID: 27057631
Therapeutic irradiation of pediatric and adult patients can profoundly affect adult neurogenesis, and cognitive impairment manifests as a deficit in hippocampal-dependent functions. Age plays a major role in susceptibility to...
16.
Kempf S, von Toerne C, Hauck S, Atkinson M, Benotmane M, Tapio S
Proteome Sci
. 2015 Nov;
13:26.
PMID: 26578848
Background: The harmful consequences of in utero irradiation on learning and memory have been recognised but the molecular mechanisms behind the damage are still unknown. Results: Using a mass spectrometry-based...
17.
Kempf S, Sepe S, von Toerne C, Janik D, Neff F, Hauck S, et al.
J Proteome Res
. 2015 Oct;
14(11):4674-86.
PMID: 26420666
Recent epidemiological data indicate that radiation doses as low as those used in computer tomography may result in long-term neurocognitive side effects. The aim of this study was to elucidate...
18.
Barjaktarovic Z, Kempf S, Sriharshan A, Merl-Pham J, Atkinson M, Tapio S
J Radiat Res
. 2015 Apr;
56(4):623-32.
PMID: 25840449
Reversible lysine acetylation is a highly regulated post-translational protein modification that is known to regulate several signaling pathways. However, little is known about the radiation-induced changes in the acetylome. In...
19.
Kempf S, Moertl S, Sepe S, von Toerne C, Hauck S, Atkinson M, et al.
J Proteome Res
. 2015 Mar;
14(5):2055-64.
PMID: 25807253
The increased use of radiation-based medical imaging methods such as computer tomography is a matter of concern due to potential radiation-induced adverse effects. Efficient protection against such detrimental effects has...
20.
Kempf S, Casciati A, Buratovic S, Janik D, von Toerne C, Ueffing M, et al.
Mol Neurodegener
. 2014 Dec;
9:57.
PMID: 25515237
Background/purpose Of The Study: Epidemiological evidence suggests that low doses of ionising radiation (≤1.0 Gy) produce persistent alterations in cognition if the exposure occurs at a young age. The mechanisms...