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Camilla Thygesen

Explore the profile of Camilla Thygesen including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 130
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Recent Articles
1.
Villadsen B, Thygesen C, Grebing M, Kempf S, Sandberg M, Jensen P, et al.
J Neurochem . 2022 Dec; 165(1):76-94. PMID: 36583241
Ceruloplasmin (Cp) is a multicopper oxidase with ferroxidase properties being of importance to the mobilisation and export of iron from cells and its ability to bind copper. In ageing humans,...
2.
Thomsen B, Madsen C, Krohn K, Thygesen C, Schutt T, Metaxas A, et al.
J Alzheimers Dis . 2021 May; 82(2):575-592. PMID: 34057083
Background: Microglia contribute to Alzheimer's disease (AD) pathogenesis by clearing amyloid-β (Aβ) and driving neuroinflammation. Domestic dogs with age-related dementia (canine cognitive dysfunction (CCD)) develop cerebral amyloidosis like humans developing...
3.
Metaxas A, Thygesen C, Briting S, Landau A, Darvesh S, Finsen B
Front Cell Neurosci . 2019 Dec; 13:538. PMID: 31866830
Sections from the middle frontal gyrus (Brodmann area 46) of autopsy-confirmed Alzheimer's disease (AD) patients and non-demented subjects were examined for the prevalence of hallmark AD pathology, including amyloid-β (Aβ)...
4.
Metaxas A, Thygesen C, Kempf S, Anzalone M, Vaitheeswaran R, Petersen S, et al.
Sci Rep . 2019 Nov; 9(1):15758. PMID: 31673052
Despite compelling evidence that the accumulation of amyloid-beta (Aβ) promotes neocortical MAPT (tau) aggregation in familial and idiopathic Alzheimer's disease (AD), murine models of cerebral amyloidosis are not considered to...
5.
Myhre C, Thygesen C, Villadsen B, Vollerup J, Ilkjaer L, Krohn K, et al.
Front Cell Neurosci . 2019 Aug; 13:308. PMID: 31417357
Insulin-like growth factor-1 (IGF-1) is a pleiotropic molecule with neurotrophic and immunomodulatory functions. Knowing the capacity of chronically activated microglia to produce IGF-1 may therefore show essential to promote beneficial...
6.
Thygesen C, Larsen M, Finsen B
Expert Rev Proteomics . 2019 Jun; 16(7):601-611. PMID: 31220951
: Inflammation is integral in the neuropathology of both chronic and acute neurological disorders. Knowing the inflammatory profile is important for clarification of disease mechanisms, diagnostic purposes, and ultimately treatment...
7.
Thygesen C, Ilkjaer L, Kempf S, Hemdrup A, von Linstow C, Babcock A, et al.
Front Cell Neurosci . 2018 Nov; 12:397. PMID: 30459560
Neuroinflammation, characterized by chronic activation of the myeloid-derived microglia, is a hallmark of Alzheimer's disease (AD). Systemic inflammation, typically resulting from infection, has been linked to the progression of AD...
8.
Thygesen C, Metaxas A, Larsen M, Finsen B
J Alzheimers Dis . 2018 Jul; 64(4):1247-1259. PMID: 29991132
Background: Alzheimer's disease (AD), the most common cause of dementia, is characterized by the intra- and extracellular aggregation and accumulation of proteins. The major molecular hallmark is the aggregation of...
9.
Thygesen C, Boll I, Finsen B, Modzel M, Larsen M
Expert Rev Proteomics . 2018 Jan; 15(3):245-258. PMID: 29376447
Exploring post-translational modifications (PTMs) with the use of mass spectrometry (PTMomics) is a rapidly developing area, with methods for discovery/quantification being developed and advanced on a regular basis. PTMs are...
10.
Metaxas A, Vaitheeswaran R, Jensen K, Thygesen C, Ilkjaer L, Darvesh S, et al.
Curr Alzheimer Res . 2017 Oct; 15(5):420-428. PMID: 28982335
Background: Although mood and sleep disturbances are nearly universal among patients with Alzheimer's disease (AD), brain structures involved in non-cognitive processing remain under characterized in terms of AD pathology. Objectives:...