Stefan Heidmann
Overview
Explore the profile of Stefan Heidmann including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
749
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Recent Articles
1.
Hellmuth S, Rata S, Brown A, Heidmann S, Novak B, Stemmann O
Mol Cell
. 2015 Apr;
58(3):495-506.
PMID: 25921067
Ring-shaped cohesin keeps sister chromatids paired until cleavage of its Scc1/Rad21 subunit by separase triggers chromosome segregation in anaphase. Vertebrate separase is held inactive by mutually exclusive binding to securin...
2.
Schittenhelm R, Althoff F, Heidmann S, Lehner C
J Cell Sci
. 2010 Oct;
123(Pt 21):3768-79.
PMID: 20940262
Propagation of centromere identity during cell cycle progression in higher eukaryotes depends critically on the faithful incorporation of a centromere-specific histone H3 variant encoded by CENPA in humans and cid...
3.
Pauli A, Althoff F, Oliveira R, Heidmann S, Schuldiner O, Lehner C, et al.
Dev Cell
. 2008 Feb;
14(2):239-51.
PMID: 18267092
Cohesin is a highly conserved multisubunit complex that holds sister chromatids together in mitotic cells. At the metaphase to anaphase transition, proteolytic cleavage of the alpha kleisin subunit (Rad21) by...
4.
Schittenhelm R, Heeger S, Althoff F, Walter A, Heidmann S, Mechtler K, et al.
Chromosoma
. 2007 Mar;
116(4):385-402.
PMID: 17333235
Chromosome segregation during meiosis and mitosis depends on the assembly of functional kinetochores within centromeric regions. Centromeric DNA and kinetochore proteins show surprisingly little sequence conservation despite their fundamental biological...
5.
Oliveira R, Heidmann S, Sunkel C
Chromosoma
. 2007 Feb;
116(3):259-74.
PMID: 17318635
The condensed state of mitotic chromosomes is crucial for faithful genome segregation. Key factors implicated in the formation of mitotic chromosomes are the condensin I and II complexes. In Drosophila,...
6.
Schuh M, Lehner C, Heidmann S
Curr Biol
. 2007 Jan;
17(3):237-43.
PMID: 17222555
The centromere/kinetochore complex is indispensable for accurate segregation of chromosomes during cell divisions when it serves as the attachment site for spindle microtubules. Centromere identity in metazoans is believed to...
7.
Heeger S, Leismann O, Schittenhelm R, Schraidt O, Heidmann S, Lehner C
Genes Dev
. 2005 Sep;
19(17):2041-53.
PMID: 16140985
Faithful transmission of genetic information during mitotic divisions depends on bipolar attachment of sister kinetochores to the mitotic spindle and on complete resolution of sister-chromatid cohesion immediately before the metaphase-to-anaphase...
8.
Pandey R, Heidmann S, Lehner C
J Cell Sci
. 2005 Jan;
118(Pt 4):733-42.
PMID: 15671062
Separase cleaves a subunit of the cohesin complex and thereby promotes sister chromatid separation during mitotic and meiotic divisions. Drosophila separase associates with regulatory subunits encoded by the pimples and...
9.
Jager H, Rauch M, Heidmann S
Chromosoma
. 2004 Dec;
113(7):350-61.
PMID: 15592865
The centromere-specific histone H3 variant CENP-A plays a crucial role in kinetochore specification and assembly. We chose a genetic approach to identify interactors of the Drosophila CENP-A homolog CID. Overexpression...
10.
Heidmann D, Horn S, Heidmann S, Schleiffer A, Nasmyth K, Lehner C
Chromosoma
. 2004 Sep;
113(4):177-87.
PMID: 15375666
Stepwise and regionally controlled resolution of sister chromatid cohesion is thought to be crucial for faithful chromosome segregation during meiotic divisions. In yeast, the meiosis-specific alpha-kleisin subunit of the cohesin...