Stefan Bohringer
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Explore the profile of Stefan Bohringer including associated specialties, affiliations and a list of published articles.
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111
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6034
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Recent Articles
1.
van der Burg L, Bohringer S, Bartlett J, Bosse T, Horeweg N, de Wreede L, et al.
Stat Med
. 2025 Mar;
44(6):e70032.
PMID: 40042406
In various missing data problems, values are not entirely missing, but are coarsened. For coarsened observations, instead of observing the true value, a subset of values - strictly smaller than...
2.
van der Burg L, Putter H, Baldauf H, Sauter J, Schetelig J, de Wreede L, et al.
Stat Methods Med Res
. 2025 Jan;
:9622802241304112.
PMID: 39885761
Missing data problems are common in biological, high-dimensional data, where data can be partially or completely missing. Algorithms have been developed to reconstruct the missing values by means of imputation...
3.
Mertens J, Hessel M, Kempen T, Bohringer S, Norbart A, Walinga C, et al.
BMC Med Educ
. 2025 Jan;
25(1):48.
PMID: 39799314
Background: Effective pharmacotherapy requires strong collaboration between physicians and pharmacists, highlighting the need for interprofessional education (IPE) in university curricula. This study evaluated the impact of an IPE program on...
4.
de Groot F, Dekker T, Doorduijn J, Bohringer S, Brink M, de Groen R, et al.
Eur J Cancer
. 2024 Oct;
213:115068.
PMID: 39427440
Given the rarity of primary central nervous system lymphoma (PCNSL), evaluations of different high-dose methotrexate-(HD-MTX)-based treatment regimens is sparse. This retrospective, multicenter study evaluates clinical characteristics and outcomes (progression-free, overall...
5.
Grit G, van Geffen E, Malmberg R, van Leeuwen R, Bohringer S, Jm Smit H, et al.
Lung Cancer
. 2024 Sep;
196:107950.
PMID: 39236576
Background: High and increasing expenses on pembrolizumab ask for more cost-effective and sustainable treatment strategies to improve affordability of healthcare. Therefore, a part of the Dutch hospitals implemented an alternative,...
6.
Knikman J, Zhai Q, Lunenburg C, Henricks L, Bohringer S, van der Lee M, et al.
Genome Med
. 2024 Aug;
16(1):101.
PMID: 39148102
Background: The Alpe-DPD study (NCT02324452) demonstrated that prospective genotyping and dose-individualization using four alleles in DPYD (DPYD*2A/rs3918290, c.1236G > A/rs75017182, c.2846A > T/rs67376798 and c.1679 T > G/rs56038477) can mitigate...
7.
Giraud E, Krens S, Bohringer S, Desar I, Vermeulen S, Kiemeney L, et al.
Br J Clin Pharmacol
. 2024 Aug;
91(2):297-305.
PMID: 39107874
Aims: Sunitinib exhibits considerable interindividual variability in exposure. While the target total plasma concentration of sunitinib and its active metabolite is 50-87.5 ng/mL for the intermittent dosing schedule, ~10-21% of...
8.
Sanchez-Spitman A, Bohringer S, Dezentje V, Gelderblom H, Swen J, Guchelaar H
Clin Pharmacol Ther
. 2024 Mar;
116(1):155-164.
PMID: 38501904
Tamoxifen is part of the standard of care of endocrine therapy for adjuvant treatment of breast cancer. However, survival outcomes with tamoxifen are highly variable. The concentration of endoxifen, the...
9.
Takase-Minegishi K, Bohringer S, Nam J, Kaneko Y, Behrens F, Saevarsdottir S, et al.
Rheumatology (Oxford)
. 2024 Feb;
64(2):548-560.
PMID: 38366945
Objective: To investigate the efficacy of bDMARDs in patients with RA with RF/ACPA compared with patients without these autoantibodies. Methods: Previous systematic literature reviews performed by EULAR RA management task...
10.
de Gruil N, Bohringer S, de Groot S, Pijl H, Kroep J, Swen J
Cancers (Basel)
. 2023 Dec;
15(24).
PMID: 38136416
Aim: We aimed to investigate associations between and single nucleotide variants (SNVs) and clinical response in patients with breast cancer treated with neoadjuvant chemotherapy with or without a fasting mimicking...