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Stefan Bohn

Explore the profile of Stefan Bohn including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 1274
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Recent Articles
1.
Kumar A, Roth J, Kim H, Saura P, Bohn S, Reif-Trauttmansdorff T, et al.
Nat Commun . 2025 Mar; 16(1):2302. PMID: 40055346
The Rnf complex is the primary respiratory enzyme of several anaerobic prokaryotes that transfers electrons from ferredoxin to NAD and pumps ions (Na or H) across a membrane, powering ATP...
2.
Bohnacker S, Henkel F, Hartung F, Geerlof A, Riemer S, Prodjinotho U, et al.
Sci Immunol . 2024 Dec; 9(102):eadl1467. PMID: 39642243
The molecular mechanisms by which worm parasites evade host immunity are incompletely understood. In a mouse model of intestinal helminth infection using (), we show that helminthic glutamate dehydrogenase (heGDH)...
3.
Sendker F, Schlotthauer T, Mais C, Lo Y, Girbig M, Bohn S, et al.
Nat Commun . 2024 Dec; 15(1):10515. PMID: 39627196
Many enzymes assemble into homomeric protein complexes comprising multiple copies of one protein. Because structural form is usually assumed to follow function in biochemistry, these assemblies are thought to evolve...
4.
Zinzula L, Beck F, Camasta M, Bohn S, Liu C, Morado D, et al.
Nat Commun . 2024 Nov; 15(1):10307. PMID: 39604358
Marburg virus (MARV) causes lethal hemorrhagic fever in humans, posing a threat to global health. We determined by cryogenic electron microscopy (cryo-EM) the MARV helical ribonucleoprotein (RNP) complex structure in...
5.
Hartmann L, Kristofori P, Li C, Becker K, Hexemer L, Bohn S, et al.
Life Sci Alliance . 2024 Nov; 8(1). PMID: 39542693
TGFβ-signaling regulates cancer progression by controlling cell division, migration, and death. These outcomes are mediated by gene expression changes, but the mechanisms of decision-making toward specific fates remain unclear. Here,...
6.
Wagner J, Carvajal A, Bracher A, Beck F, Wan W, Bohn S, et al.
Nature . 2024 Aug; 633(8029):459-464. PMID: 39169181
Chaperonins are large barrel-shaped complexes that mediate ATP-dependent protein folding. The bacterial chaperonin GroEL forms juxtaposed rings that bind unfolded protein and the lid-shaped cofactor GroES at their apertures. In...
7.
Sendker F, Schlotthauer T, Mais C, Lo Y, Girbig M, Bohn S, et al.
bioRxiv . 2024 Jul; PMID: 39005358
Many enzymes assemble into homomeric protein complexes comprising multiple copies of one protein. Because structural form is usually assumed to follow function in biochemistry, these assemblies are thought to evolve...
8.
Sendker F, Lo Y, Heimerl T, Bohn S, Persson L, Mais C, et al.
Nature . 2024 Apr; 628(8009):894-900. PMID: 38600380
Fractals are patterns that are self-similar across multiple length-scales. Macroscopic fractals are common in nature; however, so far, molecular assembly into fractals is restricted to synthetic systems. Here we report...
9.
Bohn S, Hexemer L, Huang Z, Strohmaier L, Lenhardt S, Legewie S, et al.
Proc Natl Acad Sci U S A . 2023 Mar; 120(10):e2210891120. PMID: 36857347
SMAD-mediated signaling regulates apoptosis, cell cycle arrest, and epithelial-to-mesenchymal transition to safeguard tissue homeostasis. However, it remains elusive how the relatively simple pathway can determine such a broad range of...
10.
Bohn S
Bio Protoc . 2021 Oct; 11(18):e4161. PMID: 34692911
Genome-wide sequencing of RNA (RNA-seq) has become an inexpensive tool to gain key insights into cellular and disease mechanisms. Sample preparation and sequencing are streamlined and allow the acquisition of...