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Stanley E Lazic

Explore the profile of Stanley E Lazic including associated specialties, affiliations and a list of published articles. Areas
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Articles 58
Citations 5797
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Recent Articles
11.
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, et al.
PLoS Biol . 2020 Jul; 18(7):e3000410. PMID: 32663219
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of...
12.
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, et al.
J Cereb Blood Flow Metab . 2020 Jul; 40(9):1769-1777. PMID: 32663096
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of...
13.
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, et al.
Br J Pharmacol . 2020 Jul; 177(16):3617-3624. PMID: 32662519
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of...
14.
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, et al.
BMC Vet Res . 2020 Jul; 16(1):242. PMID: 32660541
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of...
15.
Lazic S, Semenova E, Williams D
Sci Rep . 2020 Apr; 10(1):6625. PMID: 32313041
Regulatory authorities require animal toxicity tests for new chemical entities. Organ weight changes are accepted as a sensitive indicator of chemically induced organ damage, but can be difficult to interpret...
16.
Karp N, Wilson Z, Stalker E, Mooney L, Lazic S, Zhang B, et al.
Sci Rep . 2020 Apr; 10(1):6178. PMID: 32277094
Phenotypic plasticity, the ability of a living organism to respond to the environment, can lead to conclusions from experiments that are idiosyncratic to a particular environment. The level of environmental...
17.
Lazic S, Mellor J, Ashby M, Munafo M
Sci Rep . 2020 Feb; 10(1):2366. PMID: 32047274
Pseudoreplication occurs when the number of measured values or data points exceeds the number of genuine replicates, and when the statistical analysis treats all data points as independent and thus...
18.
Williams D, Lazic S, Foster A, Semenova E, Morgan P
Chem Res Toxicol . 2019 Sep; 33(1):239-248. PMID: 31535850
Drug induced liver injury (DILI) can require significant risk management in drug development and on occasion can cause morbidity or mortality, leading to drug attrition. Optimizing candidates preclinically can minimize...
19.
Adelof J, Ross J, Lazic S, Zetterberg M, Wiseman J, Hernebring M
Aging (Albany NY) . 2019 Sep; 11(17):7150-7168. PMID: 31509518
Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies. The aim of this study is to determine age-related behavioral changes of F2 hybrid...
20.
Foster A, Chouhan B, Regan S, Rollison H, Amberntsson S, Andersson L, et al.
Arch Toxicol . 2019 Mar; 93(4):1021-1037. PMID: 30915487
Drug-induced liver injury remains a frequent reason for drug withdrawal. Accordingly, more predictive and translational models are required to assess human hepatotoxicity risk. This study presents a comprehensive evaluation of...