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Stanley E Lazic

Explore the profile of Stanley E Lazic including associated specialties, affiliations and a list of published articles. Areas
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Articles 58
Citations 5797
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Recent Articles
1.
Lazic S
Psychol Methods . 2024 Nov; PMID: 39570698
Most scientific disciplines use significance testing to draw conclusions about experimental or observational data. This classical approach provides a theoretical guarantee for controlling the number of false positives across a...
2.
Lazic S
Lab Anim . 2024 Aug; 58(5):438-442. PMID: 39157973
Most classical statistical tests assume data are normally distributed. If this assumption is not met, researchers often turn to non-parametric methods. These methods have some drawbacks, and if no suitable...
3.
Lazic S
Lab Anim . 2024 Aug; 58(5):458-462. PMID: 39129196
The purpose of many preclinical studies is to determine whether an experimental intervention affects an outcome through a particular mechanism, but the analytical methods and inferential logic typically used cannot...
4.
Cairns J, Leonard E, Khan K, Parks C, Maglennon G, Zhang B, et al.
Front Pharmacol . 2023 Apr; 14:1142581. PMID: 37063297
Microphysiological systems (MPS; organ-on-a-chip) aim to recapitulate the 3D organ microenvironment and improve clinical predictivity relative to previous approaches. Though MPS studies provide great promise to explore treatment options in...
5.
Semenova E, Guerriero M, Zhang B, Hock A, Hopcroft P, Kadamur G, et al.
SLAS Discov . 2021 Sep; 26(9):1212-1224. PMID: 34543136
A proteolysis-targeting chimera (PROTAC) is a new technology that marks proteins for degradation in a highly specific manner. During screening, PROTAC compounds are tested in concentration-response (CR) assays to determine...
6.
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, et al.
BMJ Open Sci . 2021 Jun; 4(1):e100115. PMID: 34095516
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of...
7.
Weberpals J, Pugh T, Marco-Casanova P, Goss G, Andrews Wright N, Rath P, et al.
Cancer Med . 2021 Apr; 10(9):3045-3058. PMID: 33811746
Background: In high grade serous ovarian cancer (HGSOC), there is a spectrum of sensitivity to first line platinum-based chemotherapy. This study molecularly characterizes HGSOC patients from two distinct groups of...
8.
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, et al.
J Physiol . 2020 Jul; 598(18):3793-3801. PMID: 32666574
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of...
9.
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, et al.
Exp Physiol . 2020 Jul; 105(9):1459-1466. PMID: 32666546
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of...
10.
Percie du Sert N, Ahluwalia A, Alam S, Avey M, Baker M, Browne W, et al.
PLoS Biol . 2020 Jul; 18(7):e3000411. PMID: 32663221
Improving the reproducibility of biomedical research is a major challenge. Transparent and accurate reporting is vital to this process; it allows readers to assess the reliability of the findings and...