Stanislav Tomarev
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Explore the profile of Stanislav Tomarev including associated specialties, affiliations and a list of published articles.
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25
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1047
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Recent Articles
11.
Mead B, Tomarev S
Exp Eye Res
. 2016 Aug;
151:96-106.
PMID: 27523467
Retinal ganglion cells (RGC) bear the sole responsibility of propagating visual stimuli to the brain. Their axons, which make up the optic nerve, project from the retina to the brain...
12.
Chou T, Tomarev S, Porciatti V
Invest Ophthalmol Vis Sci
. 2014 Aug;
55(9):5602-9.
PMID: 25125600
Purpose: To characterize age-related changes of retinal ganglion cell (RGC) function, IOP, and anatomical markers of axon/glia integrity in a transgenic mouse expressing Tyr437His mutant of human myocilin protein. Methods:...
13.
Suntharalingam A, Abisambra J, OLeary 3rd J, Koren 3rd J, Zhang B, Joe M, et al.
J Biol Chem
. 2012 Oct;
287(48):40661-9.
PMID: 23035116
Background: Mutant myocilin accumulates in the endoplasmic reticulum for unknown reasons. Results: Glucose-regulated protein (Grp) 94 depletion reduces mutant myocilin by engaging autophagy. Conclusion: Grp94 triages mutant myocilin through ER-associated...
14.
Chi Z, Akahori M, Obazawa M, Minami M, Noda T, Nakaya N, et al.
Hum Mol Genet
. 2010 Apr;
19(13):2606-15.
PMID: 20388642
Glaucoma is one of the leading causes of bilateral blindness affecting nearly 8 million people worldwide. Glaucoma is characterized by a progressive loss of retinal ganglion cells (RGCs) and is...
15.
Nakaya N, Tomarev S
Gene Expr Patterns
. 2007 Aug;
7(7):723-9.
PMID: 17681890
Olfactomedin 1 (Olfm1) is a founding member of the family of olfactomedin domain-containing proteins. It is a secreted protein that performs different roles in different species. Although the molecular mechanisms...
16.
Senatorov V, Malyukova I, Fariss R, Wawrousek E, Swaminathan S, Sharan S, et al.
J Neurosci
. 2006 Nov;
26(46):11903-14.
PMID: 17108164
We developed a genetic mouse model of open-angle glaucoma by expression of mutated mouse myocilin (Myoc) in transgenic (Tg) mice. The Tyr423His point mutation, corresponding to the severe glaucoma-causing Tyr437His...
17.
Surgucheva I, Park B, Yue B, Tomarev S, Surguchov A
Cell Mol Neurobiol
. 2006 Jan;
25(6):1009-33.
PMID: 16392033
Mutations in the gene encoding human myocilin are associated with some cases of juvenile and early-onset glaucoma. Glaucomatous mutations prevent myocilin from being secreted. The analysis of the defects associated...
18.
Reis R, Reis-Filho J, Longatto Filho A, Tomarev S, Silva P, Lopes J
Pathol Res Pract
. 2005 Nov;
201(12):771-6.
PMID: 16308102
The study of lymphatic vessels and lymphatic tumors has been hampered with difficulty due to the overlapping morphological features between blood and lymphatic endothelial cells, as well as to the...
19.
Grinchuk O, Kozmik Z, Wu X, Tomarev S
J Biol Chem
. 2005 Aug;
280(42):35228-37.
PMID: 16115881
The Optimedin gene, also known as Olfactomedin 3, encodes an olfactomedin domain-containing protein. There are two major splice variants of the Optimedin mRNA, Optimedin A and Optimedin B, transcribed from...
20.
Wistow G, Wyatt K, David L, Gao C, Bateman O, Bernstein S, et al.
FEBS J
. 2005 Apr;
272(9):2276-91.
PMID: 15853812
The beta and gamma crystallins are evolutionarily related families of proteins that make up a large part of the refractive structure of the vertebrate eye lens. Each family has a...