Srinivas Koduru
Overview
Explore the profile of Srinivas Koduru including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
476
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0
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Recent Articles
1.
Wu Y, Hospodiuk M, Peng W, Gudapati H, Neuberger T, Koduru S, et al.
Biofabrication
. 2018 Nov;
11(1):015009.
PMID: 30468153
The scalability of cell aggregates such as spheroids, strands, and rings has been restricted by diffusion of nutrient and oxygen into their core. In this study, we introduce a novel...
2.
Das R, Strowig T, Verma R, Koduru S, Hafemann A, Hopf S, et al.
Nat Med
. 2016 Nov;
22(11):1351-1357.
PMID: 27723723
Most human cancers, including myeloma, are preceded by a precursor state. There is an unmet need for in vivo models to study the interaction of human preneoplastic cells in the...
3.
Sehgal K, Das R, Zhang L, Verma R, Deng Y, Kocoglu M, et al.
Blood
. 2015 Apr;
125(26):4042-51.
PMID: 25869284
In preclinical studies, pomalidomide mediated both direct antitumor effects and immune activation by binding cereblon. However, the impact of drug-induced immune activation and cereblon/ikaros in antitumor effects of pomalidomide in...
4.
Sehgal K, Guo X, Koduru S, Shah A, Lin A, Yan X, et al.
Sci Transl Med
. 2013 Jul;
5(193):193ra89.
PMID: 23843450
Immune thrombocytopenia (ITP) is an autoimmune disorder of childhood characterized by immune-mediated destruction of platelets. The mechanisms underlying the pathogenesis of ITP and the therapeutic efficacy of intravenous immunoglobulins (IVIG)...
5.
Koduru S, Wong E, Strowig T, Sundaram R, Zhang L, Strout M, et al.
Blood
. 2012 Jan;
119(10):2302-9.
PMID: 22234692
Tumor microenvironment (TME) is commonly implicated in regulating the growth of tumors, but whether it can directly alter the genetics of tumors is not known. Genomic instability and dendritic cell...
6.
Thirupathi Reddy Y, Narsimha Reddy P, Koduru S, Damodaran C, Crooks P
Bioorg Med Chem
. 2010 Apr;
18(10):3570-4.
PMID: 20403701
A series of substituted (Z)-5-(N-benzylindol-3-ylmethylene)imidazolidine-2,4-dione (3) analogs structurally related to aplysinopsin, and that incorporate a variety of substituents in both the indole and N-benzyl moieties have been synthesized under microwave...
7.
Koduru S, Kumar R, Srinivasan S, Evers M, Damodaran C
Mol Cancer Ther
. 2010 Jan;
9(1):202-10.
PMID: 20053782
Notch signaling plays a crucial role in the development of colon cancer; targeting the Notch pathway may sensitize colon cancers to various adjuvant agents. The focus of our current study...
8.
Srinivasan S, Kumar R, Koduru S, Chandramouli A, Damodaran C
Apoptosis
. 2009 Oct;
15(2):153-61.
PMID: 19851870
The tumor necrosis factor (TNF) receptor super family comprises of members that induce two distinct signaling cascades, leading to either cell survival or apoptosis. However, in prostate cancer (PCa), TNF-mediated...
9.
Adedapo A, Jimoh F, Koduru S, Masika P, Afolayan A
BMC Complement Altern Med
. 2009 Jul;
9:21.
PMID: 19580647
Background: Buddleja saligna Willd (Loganiaceae) is a small to medium-sized evergreen tree; trunk short, often gnarled and crooked; crown dense, rounded or domed-shaped; foliage greyish green. The wild olives are...
10.
Srinivasan S, Koduru S, Kumar R, Venguswamy G, Kyprianou N, Damodaran C
Int J Cancer
. 2009 Apr;
125(4):961-7.
PMID: 19384950
In recent years, Akt signaling has gained recognition for its functional role in more aggressive, therapy-resistant malignancies. As it is frequently constitutively active in cancer cells, several drugs are being...