Sreeja C Sekhar
Overview
Explore the profile of Sreeja C Sekhar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
110
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Puleo N, Ram H, Dziubinski M, Carvette D, Teitel J, Sekhar S, et al.
Mol Cancer Ther
. 2025 Jan;
PMID: 39873147
Up to 90% of high-grade serous ovarian cancer (HGSC) patients will develop resistance to platinum-based chemotherapy, posing substantial therapeutic challenges due to a lack of universally druggable targets. Leveraging BenevolentAI's...
2.
Venkatesh J, Muthu M, Singaravelu I, Cheriyan V, Sekhar S, Acharige N, et al.
Front Oncol
. 2024 May;
14:1376666.
PMID: 38756656
CARP-1, a perinuclear phospho-protein, regulates cell survival and apoptosis signaling induced by genotoxic drugs. However, kinase(s) phosphorylating CARP-1 and down-stream signal transduction events remain unclear. Here we find that CARP-1...
3.
Bustos M, Yokoe T, Shoji Y, Kobayashi Y, Mizuno S, Murakami T, et al.
Cell Biosci
. 2023 Nov;
13(1):200.
PMID: 37932806
Background: Poly (ADP-ribose) polymerase inhibitors (PARPi) are approved for the treatment of BRCA-mutated breast cancer (BC), including triple-negative BC (TNBC) and ovarian cancer (OvCa). A key challenge is to identify...
4.
Knarr M, Avelar R, Sekhar S, Kwiatkowski L, Dziubinski M, McAnulty J, et al.
Nat Commun
. 2020 Jun;
11(1):3231.
PMID: 32591511
Genomic instability (GI) predisposes cells to malignant transformation, however the molecular mechanisms that allow for the propagation of cells with a high degree of genomic instability remain unclear. Here we...
5.
Venkatesh J, Sekhar S, Cheriyan V, Muthu M, Meister P, Levi E, et al.
J Biol Chem
. 2020 Feb;
295(11):3532-3552.
PMID: 32024692
NF-κB is a pro-inflammatory transcription factor that critically regulates immune responses and other distinct cellular pathways. However, many NF-κB-mediated pathways for cell survival and apoptosis signaling in cancer remain to...
6.
Sekhar S, Venkatesh J, Cheriyan V, Muthu M, Levi E, Assad H, et al.
Cancers (Basel)
. 2019 Feb;
11(2).
PMID: 30769864
Cell Cycle and Apoptosis Regulatory Protein (CARP-1/CCAR1) is a peri-nuclear phosphoprotein that regulates apoptosis via chemotherapeutic Adriamycin (doxorubicin) and a novel class of CARP-1 functional mimetic (CFM) compounds. Although Adriamycin...
7.
Indu S, Sekhar S, Sengottaiyan J, Kumar A, Pillai S, Laloraya M, et al.
Mol Cell Proteomics
. 2015 Oct;
14(12):3185-95.
PMID: 26432663
DYNLT1 is a member of a gene family identified within the t-complex of the mouse, which has been linked with male germ cell development and function in the mouse and...
8.
Shigehiro T, Kasai T, Murakami M, Sekhar S, Tominaga Y, Okada M, et al.
PLoS One
. 2014 Sep;
9(9):e107976.
PMID: 25264848
Although the encapsulation of paclitaxel into liposomes has been extensively studied, its significant hydrophobic and uncharged character has generated substantial difficulties concerning its efficient encapsulation into the inner water core...
9.
El-Aarag B, Kasai T, Zahran M, Zakhary N, Shigehiro T, Sekhar S, et al.
Int Immunopharmacol
. 2014 May;
21(2):283-92.
PMID: 24859059
Inhibition of angiogenesis is currently perceived as a promising strategy in the treatment of cancer. The anti-angiogenicity of thalidomide has inspired a second wave of research on this teratogenic drug....
10.
Sekhar S, Kasai T, Satoh A, Shigehiro T, Mizutani A, Murakami H, et al.
J Cancer
. 2013 Jul;
4(5):391-401.
PMID: 23833684
The oncogenic tyrosine kinase receptor ErbB2 is a prognostic factor and target for breast cancer therapeutics. In contrast with the other ErbB receptors, ErbB2 is hardly internalized by ligand induced...