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Soujuan Wang

Explore the profile of Soujuan Wang including associated specialties, affiliations and a list of published articles. Areas
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Citations 365
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Recent Articles
1.
Brandt S, Klopfenstein N, Wang S, Winfree S, McCarthy B, Territo P, et al.
PLoS Pathog . 2018 Aug; 14(8):e1007244. PMID: 30102746
The early events that shape the innate immune response to restrain pathogens during skin infections remain elusive. Methicillin-resistant Staphylococcus aureus (MRSA) infection engages phagocyte chemotaxis, abscess formation, and microbial clearance....
2.
Sisti F, Wang S, Brandt S, Glosson-Byers N, Mayo L, Son Y, et al.
Sci Signal . 2018 May; 11(528). PMID: 29717063
Sepsis-induced organ damage is caused by systemic inflammatory response syndrome (SIRS), which results in substantial comorbidities. Therefore, it is of medical importance to identify molecular brakes that can be exploited...
3.
Long Q, Yan R, Hu J, Cai D, Mitra B, Kim E, et al.
PLoS Pathog . 2017 Dec; 13(12):e1006784. PMID: 29287110
Hepadnavirus covalently closed circular (ccc) DNA is the bona fide viral transcription template, which plays a pivotal role in viral infection and persistence. Upon infection, the non-replicative cccDNA is converted...
4.
Pineros Alvarez A, Glosson-Byers N, Brandt S, Wang S, Wong H, Sturgeon S, et al.
JCI Insight . 2017 Jul; 2(13). PMID: 28679957
Sepsis can induce an overwhelming systemic inflammatory response, resulting in organ damage and death. Suppressor of cytokine signaling 1 (SOCS1) negatively regulates signaling by cytokine receptors and Toll-like receptors (TLRs)....
5.
Zhang H, Rodriguez S, Wang L, Wang S, Serezani H, Kapur R, et al.
Stem Cell Reports . 2016 Jun; 6(6):940-956. PMID: 27264973
Toll-like receptor 4 (TLR4) plays a central role in host responses to bacterial infection, but the precise mechanism(s) by which its downstream signaling components coordinate the bone marrow response to...
6.
Wang Z, Brandt S, Medeiros A, Wang S, Wu H, Dent A, et al.
PLoS One . 2015 Feb; 10(2):e0115855. PMID: 25706647
Macrophages dictate both initiation and resolution of inflammation. During acute inflammation classically activated macrophages (M1) predominate, and during the resolution phase alternative macrophages (M2) are dominant. The molecular mechanisms involved...
7.
Filgueiras L, Brandt S, Wang S, Wang Z, Morris D, Evans-Molina C, et al.
Sci Signal . 2015 Jan; 8(361):ra10. PMID: 25628460
Type 1 diabetes mellitus (T1DM) is associated with chronic systemic inflammation and enhanced susceptibility to systemic bacterial infection (sepsis). We hypothesized that low insulin concentrations in T1DM trigger the enzyme...
8.
Wang Z, Filgueiras L, Wang S, Serezani A, Peters-Golden M, Jancar S, et al.
J Immunol . 2014 Jan; 192(5):2349-56. PMID: 24477912
MicroRNAs are known to control TLR activation in phagocytes. We have shown that leukotriene (LT) B4 (LTB4) positively regulates macrophage MyD88 expression by decreasing suppressor of cytokine signaling-1 (SOCS-1) mRNA...
9.
Xia W, Bringmann P, McClary J, Jones P, Manzana W, Zhu Y, et al.
Protein Expr Purif . 2005 Nov; 45(1):115-24. PMID: 16289982
With the recent completion of the human genome sequencing project, scientists are faced with the daunting challenge of deciphering the function of these newly found genes quickly and efficiently. Equally...
10.
Rosser M, Xia W, Hartsell S, McCaman M, Zhu Y, Wang S, et al.
Protein Expr Purif . 2005 Mar; 40(2):237-43. PMID: 15766864
With the recent completion of the human genome sequencing project, scientists now face the daunting challenge of deciphering the function of these newly found genes quickly and efficiently. For biotechnology,...