Sophie Lotersztajn
Overview
Explore the profile of Sophie Lotersztajn including associated specialties, affiliations and a list of published articles.
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89
Citations
4458
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Recent Articles
1.
Kraus N, Uschner F, Moeslein M, Schierwagen R, Gu W, Brol M, et al.
Cells
. 2024 Oct;
13(20.
PMID: 39451225
Metabolic dysfunction-associated Steatohepatitis (MASH), is a prominent cause for liver cirrhosis. MASH-cirrhosis is responsible for liver complications and there is no specific treatment. To develop new therapeutic approaches, animal models...
2.
Gilgenkrantz H, Sayegh R, Lotersztajn S
Annu Rev Pharmacol Toxicol
. 2024 Sep;
65(1):281-299.
PMID: 39259981
Liver fibrosis develops in response to chronic liver injury and is characterized by a sustained inflammatory response that leads to excessive collagen deposition by myofibroblasts. The fibrogenic response is governed...
3.
Mabire M, Gilgenkrantz H, Lotersztajn S
Med Sci (Paris)
. 2023 Sep;
39(8-9):591-593.
PMID: 37695142
No abstract available.
4.
Allaire M, Sayegh R, Mabire M, Hammoutene A, Siebert M, Caer C, et al.
JHEP Rep
. 2023 Jul;
5(8):100794.
PMID: 37520673
Background & Aims: Liver regeneration is a repair process in which metabolic reprogramming of parenchymal and inflammatory cells plays a major role. Monoacylglycerol lipase (MAGL) is an ubiquitous enzyme at...
5.
Gilgenkrantz H, Paradis V, Lotersztajn S
Hepatology
. 2023 May;
81(1):269-287.
PMID: 37212145
Progression of chronic liver injury to fibrosis, abnormal liver regeneration, and HCC is driven by a dysregulated dialog between epithelial cells and their microenvironment, in particular immune, fibroblasts, and endothelial...
6.
Mabire M, Hegde P, Hammoutene A, Wan J, Caer C, Sayegh R, et al.
Nat Commun
. 2023 Apr;
14(1):1830.
PMID: 37005415
Recent data have shown that liver fibrosis can regress even at later stages of cirrhosis and shifting the immune response from pro-inflammatory towards a resolutive profile is considered as a...
7.
Lotersztajn S, Riva A, Wang S, Dooley S, Chokshi S, Gao B
Z Gastroenterol
. 2022 Jan;
60(1):58-66.
PMID: 35042254
Chronic alcohol consumption induces stress and damage in alcohol metabolising hepatocytes, which leads to inflammatory and fibrogenic responses. Besides these direct effects, alcohol disrupts intestinal barrier functions and induces gut...
8.
9.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, et al.
Gut
. 2021 Apr;
71(4):807-821.
PMID: 33903148
Objective: We evaluated the influence of sex on the pathophysiology of non-alcoholic fatty liver disease (NAFLD). We investigated diet-induced phenotypic responses to define sex-specific regulation between healthy liver and NAFLD...
10.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...