Sophie Giorgetti-Peraldi
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Explore the profile of Sophie Giorgetti-Peraldi including associated specialties, affiliations and a list of published articles.
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23
Citations
1286
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Recent Articles
1.
Cataldi S, Aprile M, Melillo D, Mucel I, Giorgetti-Peraldi S, Cormont M, et al.
Cells
. 2022 Jan;
11(1).
PMID: 35011604
Low-grade chronic inflammation and reduced differentiation capacity are hallmarks of hypertrophic adipose tissue (AT) and key contributors of insulin resistance. We identified PPARGΔ5 as a dominant-negative splicing isoform overexpressed in...
2.
Varela-Guruceaga M, Belaidi E, Lebeau L, Aka E, Andriantsitohaina R, Giorgetti-Peraldi S, et al.
Front Physiol
. 2020 Dec;
11:565486.
PMID: 33324235
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders. In humans, an...
3.
Cambien B, Lebrigand K, Baeri A, Nottet N, Compin C, Lamit A, et al.
PLoS Pathog
. 2020 Oct;
16(10):e1008660.
PMID: 33075093
Mammary carcinoma, including triple-negative breast carcinomas (TNBC) are tumor-types for which human and canine pathologies are closely related at the molecular level. The efficacy of an oncolytic vaccinia virus (VV)...
4.
Peraldi P, Ladoux A, Giorgetti-Peraldi S, Dani C
Cells
. 2020 Oct;
9(10).
PMID: 33049976
Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs). We, and others, have shown that...
5.
Britto F, Dumas K, Giorgetti-Peraldi S, Ollendorff V, Favier F
Am J Physiol Cell Physiol
. 2020 Sep;
319(5):C807-C824.
PMID: 32877205
The Akt/mechanistic target of rapamycin (mTOR) signaling pathway governs macromolecule synthesis, cell growth, and metabolism in response to nutrients and growth factors. Regulated in development and DNA damage response (REDD)1...
6.
Dumas K, Ayachi C, Gilleron J, Lacas-Gervais S, Pastor F, Favier F, et al.
FASEB J
. 2020 Feb;
34(4):5046-5060.
PMID: 32043636
Nonalcoholic fatty liver disease is a chronic liver disease which is associated with obesity and insulin resistance. We investigated the implication of REDD1 (Regulated in development and DNA damage response-1),...
7.
Britto F, Cortade F, Belloum Y, Blaquiere M, Gallot Y, Docquier A, et al.
BMC Biol
. 2018 Jun;
16(1):65.
PMID: 29895328
Background: Skeletal muscle atrophy is a common feature of numerous chronic pathologies and is correlated with patient mortality. The REDD1 protein is currently recognized as a negative regulator of muscle...
8.
Pastor F, Dumas K, Barthelemy M, Regazzetti C, Druelle N, Peraldi P, et al.
Sci Rep
. 2017 Aug;
7(1):7023.
PMID: 28765650
In response to endotoxemia, the organism triggers an inflammatory response, and the visceral adipose tissue represents a major source of proinflammatory cytokines. The regulation of inflammation response in the adipose...
9.
Sarrazy V, Viaud M, Westerterp M, Ivanov S, Giorgetti-Peraldi S, Guinamard R, et al.
Circ Res
. 2016 Mar;
118(7):1062-77.
PMID: 26926469
Rationale: Inflamed atherosclerotic plaques can be visualized by noninvasive positron emission and computed tomographic imaging with (18)F-fluorodeoxyglucose, a glucose analog, but the underlying mechanisms are poorly understood. Objective: Here, we...
10.
Regazzetti C, Dumas K, Lacas-Gervais S, Pastor F, Peraldi P, Bonnafous S, et al.
Endocrinology
. 2014 Dec;
156(3):789-801.
PMID: 25521582
During obesity, a hypoxic state develops within the adipose tissue, resulting in insulin resistance. To understand the underlying mechanism, we analyzed the involvement of caveolae because they play a crucial...