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Soo H Teo

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Articles 28
Citations 2251
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Recent Articles
1.
Dias A, Brook M, Bancroft E, Page E, Chamberlain A, Saya S, et al.
BJUI Compass . 2023 Apr; 4(3):361-373. PMID: 37025481
Objectives: The relation of serum androgens and the development of prostate cancer (PCa) is subject of debate. Lower total testosterone (TT) levels have been associated with increased PCa detection and...
2.
Thomassen M, Mesman R, Hansen T, Menendez M, Rossing M, Esteban-Sanchez A, et al.
Hum Mutat . 2022 Aug; 43(12):1921-1944. PMID: 35979650
Skipping of BRCA2 exon 3 (∆E3) is a naturally occurring splicing event, complicating clinical classification of variants that may alter ∆E3 expression. This study used multiple evidence types to assess...
3.
Dorling L, Carvalho S, Allen J, Gonzalez-Neira A, Luccarini C, Wahlstrom C, et al.
N Engl J Med . 2021 Jan; 384(5):428-439. PMID: 33471991
Background: Genetic testing for breast cancer susceptibility is widely used, but for many genes, evidence of an association with breast cancer is weak, underlying risk estimates are imprecise, and reliable...
4.
Silvestri V, Leslie G, Barnes D, Agnarsson B, Aittomaki K, Alducci E, et al.
JAMA Oncol . 2020 Jul; 6(8):1218-1230. PMID: 32614418
Importance: The limited data on cancer phenotypes in men with germline BRCA1 and BRCA2 pathogenic variants (PVs) have hampered the development of evidence-based recommendations for early cancer detection and risk...
5.
Liu J, Prager-van der Smissen W, Collee J, Bolla M, Wang Q, Michailidou K, et al.
Sci Rep . 2020 Jun; 10(1):9688. PMID: 32546843
In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is...
6.
Page E, Bancroft E, Brook M, Assel M, Hassan Al Battat M, Thomas S, et al.
Eur Urol . 2019 Sep; 76(6):831-842. PMID: 31537406
Background: Mutations in BRCA2 cause a higher risk of early-onset aggressive prostate cancer (PrCa). The IMPACT study is evaluating targeted PrCa screening using prostate-specific-antigen (PSA) in men with germline BRCA1/2...
7.
Dork T, Peterlongo P, Mannermaa A, Bolla M, Wang Q, Dennis J, et al.
Sci Rep . 2019 Aug; 9(1):12524. PMID: 31467304
Fanconi anemia (FA) is a genetically heterogeneous disorder with 22 disease-causing genes reported to date. In some FA genes, monoallelic mutations have been found to be associated with breast cancer...
8.
Parsons M, Tudini E, Li H, Hahnen E, Wappenschmidt B, Feliubadalo L, et al.
Hum Mutat . 2019 May; 40(9):1557-1578. PMID: 31131967
The multifactorial likelihood analysis method has demonstrated utility for quantitative assessment of variant pathogenicity for multiple cancer syndrome genes. Independent data types currently incorporated in the model for assessing BRCA1...
9.
Ugai T, Milne R, Ito H, Aronson K, Bolla M, Chan T, et al.
Mol Genet Genomic Med . 2019 May; 7(6):e707. PMID: 31066241
Background: Epidemiological studies consistently indicate that alcohol consumption is an independent risk factor for female breast cancer (BC). Although the aldehyde dehydrogenase 2 (ALDH2) polymorphism (rs671: Glu>Lys) has a strong...
10.
Qian F, Wang S, Mitchell J, McGuffog L, Barrowdale D, Leslie G, et al.
J Natl Cancer Inst . 2018 Oct; 111(4):350-364. PMID: 30312457
Background: BRCA1/2 mutations confer high lifetime risk of breast cancer, although other factors may modify this risk. Whether height or body mass index (BMI) modifies breast cancer risk in BRCA1/2...