Soo H Teo
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Explore the profile of Soo H Teo including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Lu Y, Beeghly-Fadiel A, Wu L, Guo X, Li B, Schildkraut J, et al.
Cancer Res
. 2018 Jul;
78(18):5419-5430.
PMID: 30054336
Large-scale genome-wide association studies (GWAS) have identified approximately 35 loci associated with epithelial ovarian cancer (EOC) risk. The majority of GWAS-identified disease susceptibility variants are located in noncoding regions, and...
12.
The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity
Colombo M, Lopez-Perolio I, Meeks H, Caleca L, Parsons M, Li H, et al.
Hum Mutat
. 2018 Feb;
39(5):729-741.
PMID: 29460995
Although the spliceogenic nature of the BRCA2 c.68-7T > A variant has been demonstrated, its association with cancer risk remains controversial. In this study, we accurately quantified by real-time PCR...
13.
Michailidou K, Lindstrom S, Dennis J, Beesley J, Hui S, Kar S, et al.
Nature
. 2017 Oct;
551(7678):92-94.
PMID: 29059683
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer...
14.
Milne R, Kuchenbaecker K, Michailidou K, Beesley J, Kar S, Lindstrom S, et al.
Nat Genet
. 2017 Oct;
49(12):1767-1778.
PMID: 29058716
Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease. We conducted a GWAS using 21,468 ER-negative cases and 100,594...
15.
Shimelis H, Mesman R, von Nicolai C, Ehlen A, Guidugli L, Martin C, et al.
Cancer Res
. 2017 Mar;
77(11):2789-2799.
PMID: 28283652
Breast cancer risks conferred by many germline missense variants in the and genes, often referred to as variants of uncertain significance (VUS), have not been established. In this study, associations...
16.
Wen W, Shu X, Guo X, Cai Q, Long J, Bolla M, et al.
Breast Cancer Res
. 2016 Dec;
18(1):124.
PMID: 27931260
Background: Approximately 100 common breast cancer susceptibility alleles have been identified in genome-wide association studies (GWAS). The utility of these variants in breast cancer risk prediction models has not been...
17.
Liu J, Loncar I, Collee J, Bolla M, Dennis J, Michailidou K, et al.
Sci Rep
. 2016 Nov;
6:36874.
PMID: 27845421
NBS1, also known as NBN, plays an important role in maintaining genomic stability. Interestingly, rs2735383 G > C, located in a microRNA binding site in the 3'-untranslated region (UTR) of...
18.
Ghoussaini M, French J, Michailidou K, Nord S, Beesley J, Canisus S, et al.
Am J Hum Genet
. 2016 Sep;
99(4):903-911.
PMID: 27640304
Genome-wide association studies (GWASs) have revealed increased breast cancer risk associated with multiple genetic variants at 5p12. Here, we report the fine mapping of this locus using data from 104,660...
19.
Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, et al.
Nat Commun
. 2016 Sep;
7:12675.
PMID: 27601076
A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases,...
20.
Darabi H, Beesley J, Droit A, Kar S, Nord S, Moradi Marjaneh M, et al.
Sci Rep
. 2016 Sep;
6:32512.
PMID: 27600471
Genome-wide association studies have found SNPs at 17q22 to be associated with breast cancer risk. To identify potential causal variants related to breast cancer risk, we performed a high resolution...