Song-Mao Chiu
Overview
Explore the profile of Song-Mao Chiu including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
333
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0
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Recent Articles
1.
Kunos C, Radivoyevitch T, Pink J, Chiu S, Stefan T, Jacobberger J, et al.
Radiat Res
. 2010 Oct;
174(5):574-81.
PMID: 20954859
For repair of damaged DNA, cells increase de novo synthesis of deoxyribonucleotide triphosphates through the rate-limiting, p53-regulated ribonucleotide reductase (RNR) enzyme. In this study we investigated whether pharmacological inhibition of...
2.
Chiu S, Xue L, Lam M, Rodriguez M, Zhang P, Kenney M, et al.
Photochem Photobiol
. 2010 Jun;
86(5):1161-73.
PMID: 20553412
Photodynamic therapy (PDT) with lysosome-targeted photosensitizers induces the intrinsic pathway of apoptosis via the cleavage and activation of the BH3-only protein Bid by proteolytic enzymes released from photodisrupted lysosomes. To...
3.
Xue L, Chiu S, Oleinick N
Autophagy
. 2010 Jan;
6(2):248-55.
PMID: 20083906
Photodynamic therapy (PDT) uses a photosensitizer, light and oxygen to produce extensive oxidative damage to organelles housing the photosensitizer. Although PDT is an efficient trigger of apoptosis, it also induces...
4.
Fei B, Wang H, Wu C, Chiu S
J Nucl Med
. 2009 Dec;
51(1):130-8.
PMID: 20008981
Unlabelled: Photodynamic therapy (PDT) is a relatively new therapy that has shown promise for treating various cancers in both preclinical and clinical studies. The present study evaluated the potential use...
5.
Kunos C, Chiu S, Pink J, Kinsella T
Radiat Res
. 2009 Nov;
172(6):666-76.
PMID: 19929413
Therapeutic ionizing radiation damages DNA, increasing p53-regulated ribonucleotide reductase (RNR) activity required for de novo synthesis of the deoxyribonucleotide triphosphates used during DNA repair. This study investigated the pharmacological inhibition...
6.
Rodriguez M, Zhang P, Azizuddin K, Delos Santos G, Chiu S, Xue L, et al.
Photochem Photobiol
. 2009 Jun;
85(5):1189-200.
PMID: 19508642
The phthalocyanine photosensitizer Pc 4 has been shown to bind preferentially to mitochondrial and endoplasmic reticulum membranes. Upon photoirradiation of Pc 4-loaded cells, membrane components, especially Bcl-2, are photodamaged and...
7.
Rodriguez M, Azizuddin K, Zhang P, Chiu S, Lam M, Kenney M, et al.
Mitochondrion
. 2008 Jun;
8(3):237-46.
PMID: 18514589
10-N-Nonyl acridine orange (NAO) is used as a mitochondrial probe because of its high affinity for cardiolipin (CL). Targeting of NAO may also depend on mitochondrial membrane potential. As the...
8.
Xue L, Chiu S, Azizuddin K, Joseph S, Oleinick N
Autophagy
. 2007 Nov;
4(1):125-7.
PMID: 18025862
Photodynamic therapy (PDT) induces apoptosis in many cell types. Recent reports identified autophagy as an alternative cell-death process following PDT. Here we investigated the occurrence of autophagy after PDT with...
9.
Xue L, Chiu S, Azizuddin K, Joseph S, Oleinick N
Photochem Photobiol
. 2007 Sep;
83(5):1016-23.
PMID: 17880494
Photodynamic therapy (PDT) is an efficient inducer of apoptosis in many types of cells, except in cells deficient in one or more of the factors that mediate apoptosis. Recent reports...
10.
Differential responses of Mcl-1 in photosensitized epithelial vs lymphoid-derived human cancer cells
Xue L, Chiu S, Oleinick N
Oncogene
. 2005 Jul;
24(46):6987-92.
PMID: 16007152
The antiapoptotic Bcl-2-family proteins, Bcl-2 and Bcl-xL, are recognized phototargets of photodynamic therapy (PDT) with the mitochondrion-targeting phthalocyanine photosensitizer Pc 4. In the present study, we found that myeloid cell...