Somanathapura K NaveenKumar
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Explore the profile of Somanathapura K NaveenKumar including associated specialties, affiliations and a list of published articles.
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304
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Recent Articles
11.
Chakrabarty G, NaveenKumar S, Kumar S, Mugesh G
ACS Chem Biol
. 2020 Sep;
15(10):2673-2682.
PMID: 32915529
Red blood cell death or erythrocyte apoptosis (eryptosis) is generally mediated by oxidative stress, energy depletion, heavy metals exposure, or xenobiotics. As erythrocytes are a major target for oxidative stress...
12.
NaveenKumar S, Hemshekhar M, Jagadish S, Manikanta K, Vishalakshi G, Kemparaju K, et al.
J Pineal Res
. 2020 Jun;
69(3):e12676.
PMID: 32597503
Melatonin is a chronobiotic hormone, which can regulate human diseases like cancer, atherosclerosis, respiratory disorders, and microbial infections by regulating redox system. Melatonin exhibits innate immunomodulation by communicating with immune...
13.
Swethakumar B, NaveenKumar S, Girish K, Kemparaju K
Biochim Biophys Acta Gen Subj
. 2020 Feb;
1864(6):129561.
PMID: 32068016
Background: Neutrophils are the first line defense cells of the innate immunity. As a final defense, they discharge their de-condensed chromatin/DNA fibers, the NETs (Neutrophil Extracellular Traps), by a process...
14.
NaveenKumar S, Hemshekhar M, Kemparaju K, Girish K
Biochim Biophys Acta Mol Basis Dis
. 2019 May;
1865(9):2303-2316.
PMID: 31102787
Reactive oxygen species (ROS) are capable of inducing cell death or apoptosis. Recently, we demonstrated that lipid-ROS can mediate ferroptosis and activation of human platelets. Ferroptosis is an intracellular iron-mediated...
15.
Vishalakshi G, NaveenKumar S, Hemshekhar M, Mahendra M, Kemparaju K, Girish K
Environ Toxicol
. 2018 Nov;
34(3):262-270.
PMID: 30461186
The catecholic derivative para-tertiary butyl catechol (PTBC) is a conventional antioxidant and polymerization inhibitor, which exhibits melanocytotoxic effects and contact dermatitis often leading to occupational leucoderma or vitiligo. Although numerous...
16.
NaveenKumar S, Sharathbabu B, Hemshekhar M, Kemparaju K, Girish K, Mugesh G
ACS Chem Biol
. 2018 Jun;
13(8):1996-2002.
PMID: 29869870
Hemolysis, a process by which the destruction of red blood cells leads to the release of hemoglobin, is a critical event observed during hemolytic disorders. Under oxidative stress conditions, hemoglobin...
17.
Swethakumar B, NaveenKumar S, Katkar G, Girish K, Kemparaju K
Biochim Biophys Acta Gen Subj
. 2018 Feb;
1862(5):1115-1125.
PMID: 29425807
Background: E. carinatus bite is a serious threat to South-Asian countries including India, as it causes the highest number of deaths and debilitating sustained tissue necrosis at the bite site....
18.
Jagadish S, Hemshekhar M, NaveenKumar S, Sharath Kumar K, Sundaram M, Basappa , et al.
Toxicol Appl Pharmacol
. 2017 Sep;
334:167-179.
PMID: 28911973
Chronic hyperglycemia is one of the characteristic conditions associated with Diabetes Mellitus (DM), which often exerts deleterious effects on erythrocyte morphology and hemodynamic properties leading to anemia and diabetes-associated vascular...
19.
NaveenKumar S, Hemshekhar M, Sundaram M, Kemparaju K, Girish K
Biochem Biophys Res Commun
. 2017 Jul;
491(1):183-191.
PMID: 28712866
Cell-free hemoglobin (Hb), a well-known marker of intravascular hemolysis, is eventually oxidized to methemoglobin (MtHb). Elevated levels of MtHb have been noted, alongside depleted levels of platelets, in several hemolytic...
20.
Katkar G, Sundaram M, NaveenKumar S, Swethakumar B, Sharma R, Paul M, et al.
Nat Commun
. 2016 Apr;
7:11361.
PMID: 27093631
Indian Echis carinatus bite causes sustained tissue destruction at the bite site. Neutrophils, the major leukocytes in the early defence process, accumulate at the bite site. Here we show that...