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Solip Park

Explore the profile of Solip Park including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 300
Followers 0
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Recent Articles
1.
Song S, Koh Y, Kim S, Lee S, Kim H, Ko J, et al.
Genome Med . 2023 Dec; 15(1):107. PMID: 38143269
Background: Despite the acceleration of somatic driver gene discovery facilitated by recent large-scale tumor sequencing data, the contribution of inherited variants remains largely unexplored, primarily focusing on previously known cancer...
2.
Koh Y, Kim H, Joo S, Song S, Choi Y, Kim H, et al.
J Transl Med . 2023 Oct; 21(1):730. PMID: 37848935
Background: Lysosomes are closely linked to autophagic activity, which plays a vital role in pancreatic ductal adenocarcinoma (PDAC) biology. The survival of PDAC patients is still poor, and the identification...
3.
Vali-Pour M, Park S, Espinosa-Carrasco J, Ortiz-Martinez D, Lehner B, Supek F
Nat Commun . 2023 Sep; 14(1):5448. PMID: 37673928
No abstract available.
4.
Vali-Pour M, Park S, Espinosa-Carrasco J, Ortiz-Martinez D, Lehner B, Supek F
Nat Commun . 2022 Jun; 13(1):3724. PMID: 35764656
Somatic mutations are an inevitable component of ageing and the most important cause of cancer. The rates and types of somatic mutation vary across individuals, but relatively few inherited influences...
5.
Park S, Supek F, Lehner B
Nat Commun . 2021 Dec; 12(1):7051. PMID: 34862370
The classic two-hit model posits that both alleles of a tumor suppressor gene (TSG) must be inactivated to cause cancer. In contrast, for some oncogenes and haploinsufficient TSGs, a single...
6.
Herranz-Montoya I, Park S, Djouder N
iScience . 2021 Nov; 24(11):103273. PMID: 34761191
Prefoldins (PFDNs) are evolutionary conserved co-chaperones, initially discovered in archaea but universally present in eukaryotes. PFDNs are prevalently organized into hetero-hexameric complexes. Although they have been overlooked since their discovery...
7.
Kwon H, Das R, Jung G, Lee H, Lee S, Berry S, et al.
J Am Chem Soc . 2021 Apr; 143(15):5836-5844. PMID: 33834782
The identification of each cell type is essential for understanding multicellular communities. Antibodies set as biomarkers have been the main toolbox for cell-type recognition, and chemical probes are emerging surrogates....
8.
Diaz-Gay M, Franch-Exposito S, Arnau-Collell C, Park S, Supek F, Munoz J, et al.
Cancers (Basel) . 2019 Mar; 11(3). PMID: 30871259
Colorectal cancer (CRC) shows aggregation in some families but no alterations in the known hereditary CRC genes. We aimed to identify new candidate genes which are potentially involved in germline...
9.
Park S, Supek F, Lehner B
Nat Commun . 2018 Jul; 9(1):2601. PMID: 29973584
The genetic causes of cancer include both somatic mutations and inherited germline variants. Large-scale tumor sequencing has revolutionized the identification of somatic driver alterations but has had limited impact on...
10.
Park S, Lehner B
Mol Syst Biol . 2015 Aug; 11(7):824. PMID: 26227665
Cancers, like many diseases, are normally caused by combinations of genetic alterations rather than by changes affecting single genes. It is well established that the genetic alterations that drive cancer...