Sohini Ramachandran
Overview
Explore the profile of Sohini Ramachandran including associated specialties, affiliations and a list of published articles.
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48
Citations
2969
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Recent Articles
1.
Liu X, Crawford L, Ramachandran S
bioRxiv
. 2025 Feb;
PMID: 39990474
A fundamental goal of genetics is to identify which and how genetic variants are associated with a trait, often using the regression results from genome-wide association (GWA) studies. Important methodological...
2.
Moody N, Williams C, Ramachandran S, Fuxjager M
PLoS Comput Biol
. 2025 Jan;
21(1):e1012740.
PMID: 39854567
Negotiating social dynamics among allies and enemies is a complex problem that often requires individuals to tailor their behavioral approach to a specific situation based on environmental and/or social factors....
3.
Chevy E, Min J, Caudill V, Champer S, Haller B, Rehmann C, et al.
bioRxiv
. 2024 Aug;
PMID: 39091875
Individual-based simulation has become an increasingly crucial tool for many fields of population biology. However, continuous geography is important to many applications, and implementing realistic and stable simulations in continuous...
4.
Smith S, Darnell G, Udwin D, Stamp J, Harpak A, Ramachandran S, et al.
Elife
. 2024 Jun;
13.
PMID: 38913556
LD score regression (LDSC) is a method to estimate narrow-sense heritability from genome-wide association study (GWAS) summary statistics alone, making it a fast and popular approach. In this work, we...
5.
Williams C, OConnell J, Freyman W, Gignoux C, Ramachandran S, Williams A
bioRxiv
. 2024 May;
PMID: 38766004
Haplotype phasing, the process of determining which genetic variants are physically located on the same chromosome, is crucial for various genetic analyses. In this study, we first benchmark SHAPEIT and...
6.
Shahamatdar S, Saeed-Vafa D, Linsley D, Khalil F, Lovinger K, Li L, et al.
Histopathology
. 2024 Apr;
85(1):116-132.
PMID: 38556922
Aims: Deep learning holds immense potential for histopathology, automating tasks that are simple for expert pathologists and revealing novel biology for tasks that were previously considered difficult or impossible to...
7.
Lappalainen T, Li Y, Ramachandran S, Gusev A
Cell
. 2024 Mar;
187(5):1059-1075.
PMID: 38428388
Human genetics has emerged as one of the most dynamic areas of biology, with a broadening societal impact. In this review, we discuss recent achievements, ongoing efforts, and future challenges...
8.
Chevy E, Huerta-Sanchez E, Ramachandran S
PLoS Genet
. 2023 Aug;
19(8):e1010399.
PMID: 37578977
Evidence of interbreeding between archaic hominins and humans comes from methods that infer the locations of segments of archaic haplotypes, or 'archaic coverage' using the genomes of people living today....
9.
Ahlquist K, Sugden L, Ramachandran S
PLoS Comput Biol
. 2023 May;
19(5):e1011175.
PMID: 37235578
Machine learning tools have proven useful across biological disciplines, allowing researchers to draw conclusions from large datasets, and opening up new opportunities for interpreting complex and heterogeneous biological data. Alongside...
10.
Carlson J, Henn B, Al-Hindi D, Ramachandran S
Nature
. 2022 Oct;
610(7932):444-447.
PMID: 36261568
No abstract available.