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» Authors » Soad A M El-Hawash

Soad A M El-Hawash

Explore the profile of Soad A M El-Hawash including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 110
Followers 0
Related Specialties
Chemistry
Pharmacy
Biochemistry
Top 10 Co-Authors
Abeer E Abdel Wahab
Nargues S Habib
Samia M Rida
Omaima G Shaaban
Raafat Soliman
Hesham T Y Fahmy
Amal M Youssef
Mona H Badr
Aly A Hazzaa
Perihan A S Elzahhar
Published In
Med Chem
Arch Pharm (Weinheim)
Eur J Med Chem
Bioorg Chem
Arch Pharm Res
Affiliations
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Recent Articles
1.
Synthesis of pyrazolo-1,2,4-triazolo[4,3-a]quinoxalines as antimicrobial agents with potential inhibition of DHPS enzyme
El-Attar M, Elbayaa R, Shaaban O, Habib N, Abdel Wahab A, Abdelwahab I, et al.
Future Med Chem . 2018 Aug; 10(18):2155-2175. PMID: 30088415
Aim: The development of a new class of antimicrobial agents is the optimal lifeline to scrap the escalating jeopardy of drug resistance. Experimental: This study aims to design and synthesize...
2.
Design, synthesis, antibacterial evaluation and molecular docking studies of some new quinoxaline derivatives targeting dihyropteroate synthase enzyme
El-Attar M, Elbayaa R, Shaaban O, Habib N, Abdel Wahab A, Abdelwahab I, et al.
Bioorg Chem . 2017 Dec; 76:437-448. PMID: 29275262
Development of new antimicrobial agents is a good solution to overcome drug-resistance problems. From this perspective, new quinoxaline derivatives bearing various bioactive heterocyclic moieties (thiadiazoles, oxadiazoles, pyrazoles and thiazoles) were...
3.
New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study
El-Miligy M, Hazzaa A, El-Messmary H, Nassra R, M El-Hawash S
Bioorg Chem . 2017 Apr; 72:102-115. PMID: 28390993
New molecular hybrids combining benzothiophene or its bioisostere benzofuran with rhodanine were synthesized as potential dual COX-2/5-LOX inhibitors. The benzothiophene or benzofuran scaffold was linked at position -2 with rhodanine...
4.
Design, synthesis and antimicrobial evaluation of methyl pyridyl-2,4- dioxobutanoates and some new derived ring systems
Elzahhar P, Soliman R, M El-Hawash S, Ragab H, Youssef A, Abdel Wahab A
Med Chem . 2014 Dec; 11(4):407-14. PMID: 25478930
This work describes the synthesis of new series of compounds derived from methyl pyridyl- 2,4-dioxobutanoates that contain pyridine ring attached to substituted bioactive heterocyclic moieties in order to investigate their...
5.
Synthesis, antioxidant, anticancer and antiviral activities of novel quinoxaline hydrazone derivatives and their acyclic C-nucleosides
El-Tombary A, M El-Hawash S
Med Chem . 2013 Oct; 10(5):521-32. PMID: 24151878
The present investigation describes the synthesis of a new series of aldehydo-sugar-N-(3-phenylquinoxalin-2- yl)hydrazones 3a-d and their acyclic C-nucleoside analogs, 1-(4-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-1-yl)alditols 7ad by using 2-hydrazino-3-phenylquinoxaline 1 as key intermediate. The synthesized...
6.
Design, synthesis and biological screening of some pyridinylpyrazole and pyridinylisoxazole derivatives as potential anti-inflammatory, analgesic, antipyretic and antimicrobial agents
M El-Hawash S, Soliman R, Youssef A, Ragab H, Elzahhar P, El-Ashmawey I, et al.
Med Chem . 2013 Sep; 10(3):318-38. PMID: 24032466
A series of substituted pyridinylpyrazole (or isoxazole) derivatives were synthesized and evaluated for their anti-inflammatory (AI) activity using formalin-induced paw edema bioassays. Their inhibitory activities of cyclooxygenase-1 and cyclooxygenase-2 (COX-1...
7.
Synthesis and biological evaluation of some novel thieno[2,3-d] pyrimidine derivatives as potential anti-inflammatory and analgesic agents
El-Tombary A, M El-Hawash S, Habib N, Soliman R, El-Ashmawy I, Shaaban O
Med Chem . 2013 May; 9(8):1099-112. PMID: 23628080
A novel series of thienopyrimidine derivatives bearing various substituents or linked to various heterocyclic moieties through atoms spacers were prepared starting from 5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6- carboxamide potassium salt 3. Twelve out of...
8.
Synthesis of some novel substituted purine derivatives as potential anticancer, anti-HIV-1 and antimicrobial agents
Rida S, Ashour F, M El-Hawash S, El-Semary M, Badr M
Arch Pharm (Weinheim) . 2007 Mar; 340(4):185-94. PMID: 17351964
In search of novel purine antimetabolites, a series of 8-substituted methylxanthine derivatives was prepared in order to explore their in vitro anticancer, anti-HIV-1 and antimicrobial activities. The target compounds include:...
9.
Synthesis of novel benzofuran and related benzimidazole derivatives for evaluation of in vitro anti-HIV-1, anticancer and antimicrobial activities
Rida S, M El-Hawash S, Fahmy H, Hazzaa A, El-Meligy M
Arch Pharm Res . 2006 Nov; 29(10):826-33. PMID: 17121175
Previously, we synthesized and evaluated several benzofuran derivatives containing heterocyclic ring substituents linked to the benzofuran nucleus at C-2 by a two- to four-atom spacer as potential anti-HIV-1, anticancer and...
10.
Synthesis of some new quinoxalines and 1,2,4-triazolo[4,3-a]-quinoxalines for evaluation of in vitro antitumor and antimicrobial activities
M El-Hawash S, Habib N, Kassem M
Arch Pharm (Weinheim) . 2006 Sep; 339(10):564-71. PMID: 17009301
Two novel series of quinoxalines derived from 3-phenylquinoxalin-2(1H)-one and 2-hydrazino-3-phenylquinoxaline, namely 1-substituted-3-phenylquinoxaline-2(1H)-ones, 2a-c, 3a-d, and 4; 2-(3-oxo-3,3a,4,5,6,7-hexahydroindazol-2-yl)-3-phenylquinoxaline 6; N- cyclopentylidene or benzylidene-N'-(3-phenylquinoxaline-2-yl)hydrazines, 7 and 18; 1-substituted-4-phenyl-1,2,4-triazolo[4,3-a]quinoxalines, 9, 10, 12, 13,...