Smitha J Sasindran
Overview
Explore the profile of Smitha J Sasindran including associated specialties, affiliations and a list of published articles.
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14
Citations
474
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Recent Articles
1.
Moliva J, Duncan M, Olmo-Fontanez A, Akhter A, Arnett E, Scordo J, et al.
J Infect Dis
. 2019 Mar;
220(3):514-523.
PMID: 30923818
As we age, there is an increased risk for the development of tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) infection. Few studies consider that age-associated changes in the alveolar lining...
2.
Clary G, Sasindran S, Nesbitt N, Mason L, Cole S, Azad A, et al.
Antimicrob Agents Chemother
. 2018 Jan;
62(3).
PMID: 29311080
has emerged as an important pathogen in people with chronic inflammatory lung diseases such as cystic fibrosis, and recent reports suggest that it may be transmissible by fomites. exhibits two...
3.
Scordo J, Arcos J, Kelley H, Diangelo L, Sasindran S, Youngmin E, et al.
Front Immunol
. 2017 Apr;
8:307.
PMID: 28373877
In 2016, the World Health Organization reported that one person dies of tuberculosis (TB) every 21 s. A host environment that () finds during its route of infection is the...
4.
Arcos J, Diangelo L, Scordo J, Sasindran S, Moliva J, Turner J, et al.
J Infect Dis
. 2015 Mar;
212(6):948-58.
PMID: 25748325
We have shown that human alveolar lining fluid (ALF) contains homeostatic hydrolases capable of altering the Mycobacterium tuberculosis cell wall and subsequently its interaction with human macrophages. Neutrophils are also...
5.
Moliva J, Rajaram M, Sidiki S, Sasindran S, Guirado E, Pan X, et al.
Age (Dordr)
. 2014 Mar;
36(3):9633.
PMID: 24584696
As we age, there is an increased risk for the development of pulmonary diseases, including infections, but few studies have considered changes in lung surfactant and components of the innate...
6.
Saikolappan S, Estrella J, Sasindran S, Khan A, Armitige L, Jagannath C, et al.
PLoS One
. 2012 May;
7(5):e36198.
PMID: 22574140
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is the leading cause of death due to bacterial infections in mankind, and BCG, an attenuated strain of Mycobacterium bovis, is an approved...
7.
Saikolappan S, Das K, Sasindran S, Jagannath C, Dhandayuthapani S
Tuberculosis (Edinb)
. 2011 Nov;
91 Suppl 1:S119-27.
PMID: 22088319
Bacterial antioxidants play a critical role in the detoxification of endogenously and host derived oxidative radicals during host-pathogen interactions. Recently, the osmotically induced bacterial protein C (OsmC) is included in...
8.
Sasindran S, Torrelles J
Front Microbiol
. 2011 Jun;
2:2.
PMID: 21687401
Tuberculosis is still a major health problem in the world. Initial interactions between Mycobacterium tuberculosis and the host mark the pathway of infection and the subsequent host inflammatory response. This...
9.
Arcos J, Sasindran S, Fujiwara N, Turner J, Schlesinger L, Torrelles J
J Immunol
. 2011 May;
187(1):372-81.
PMID: 21602490
Pulmonary surfactant contains homeostatic and antimicrobial hydrolases. When Mycobacterium tuberculosis is initially deposited in the terminal bronchioles and alveoli, as well as following release from lysed macrophages, bacilli are in...
10.
Sasindran S, Saikolappan S, Scofield V, Dhandayuthapani S
BMC Microbiol
. 2011 Mar;
11:43.
PMID: 21352546
Background: Obg is a highly conserved GTP-binding protein that has homologues in bacteria, archaea and eukaryotes. In bacteria, Obg proteins are essential for growth, and they participate in spore formation,...