Siyuan John Liu
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Explore the profile of Siyuan John Liu including associated specialties, affiliations and a list of published articles.
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11
Citations
1892
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Recent Articles
1.
He D, Wu D, Muller S, Wang L, Saha P, Ahanger S, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(13).
PMID: 33758101
Among the large, diverse set of mammalian long noncoding RNAs (lncRNAs), long noncoding primary microRNAs (lnc-pri-miRNAs) are those that host miRNAs. Whether lnc-pri-miRNA loci have important biological function independent of...
2.
Bhaduri A, Di Lullo E, Jung D, Muller S, Crouch E, Espinosa C, et al.
Cell Stem Cell
. 2020 Jan;
26(1):48-63.e6.
PMID: 31901251
Glioblastoma is a devastating form of brain cancer. To identify aspects of tumor heterogeneity that may illuminate drivers of tumor invasion, we created a glioblastoma tumor cell atlas with single-cell...
3.
Andersen R, Hong S, Lim J, Cui M, Harpur B, Hwang E, et al.
Dev Cell
. 2019 May;
49(4):632-642.e7.
PMID: 31112699
While it is now appreciated that certain long noncoding RNAs (lncRNAs) have important functions in cell biology, relatively few have been shown to regulate development in vivo, particularly with genetic...
4.
Nowakowski T, Bhaduri A, Pollen A, Alvarado B, Mostajo-Radji M, Di Lullo E, et al.
Science
. 2017 Dec;
358(6368):1318-1323.
PMID: 29217575
Systematic analyses of spatiotemporal gene expression trajectories during organogenesis have been challenging because diverse cell types at different stages of maturation and differentiation coexist in the emerging tissues. We identified...
5.
Muller S, Liu S, Di Lullo E, Malatesta M, Pollen A, Nowakowski T, et al.
Mol Syst Biol
. 2016 Nov;
12(11):889.
PMID: 27888226
Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain tumor. Epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) receptors are frequently amplified and/or possess gain-of-function...
6.
Liu S, Nowakowski T, Pollen A, Lui J, Horlbeck M, Attenello F, et al.
Genome Biol
. 2016 Apr;
17:67.
PMID: 27081004
Background: Long non-coding RNAs (lncRNAs) comprise a diverse class of transcripts that can regulate molecular and cellular processes in brain development and disease. LncRNAs exhibit cell type- and tissue-specific expression,...
7.
Pollen A, Nowakowski T, Chen J, Retallack H, Sandoval-Espinosa C, Nicholas C, et al.
Cell
. 2015 Sep;
163(1):55-67.
PMID: 26406371
Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular zone and outer subventricular zone. Although outer subventricular zone radial glia may generate the...
8.
Ramos A, Andersen R, Liu S, Nowakowski T, Hong S, Gertz C, et al.
Cell Stem Cell
. 2015 Mar;
16(4):439-447.
PMID: 25800779
While thousands of long noncoding RNAs (lncRNAs) have been identified, few lncRNAs that control neural stem cell (NSC) behavior are known. Here, we identify Pinky (Pnky) as a neural-specific lncRNA...
9.
Park D, Hong S, Salinas R, Liu S, Sun S, Sgualdino J, et al.
Cell Rep
. 2014 Sep;
8(5):1290-9.
PMID: 25176653
The epigenetic mechanisms that enable lifelong neurogenesis from neural stem cells (NSCs) in the adult mammalian brain are poorly understood. Here, we show that JMJD3, a histone H3 lysine 27...
10.
Thomson M, Liu S, Zou L, Smith Z, Meissner A, Ramanathan S
Cell
. 2011 Jun;
145(6):875-89.
PMID: 21663792
Cell fate decisions are fundamental for development, but we do not know how transcriptional networks reorganize during the transition from a pluripotent to a differentiated cell state. Here, we asked...