Sivakama Bharathi
Overview
Explore the profile of Sivakama Bharathi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
93
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Singh S, Bruder A, Costa R, Alves J, Bharathi S, Goetzman E, et al.
J Am Heart Assoc
. 2025 Feb;
14(3):e037640.
PMID: 39895524
Background: The complex interplay between vascular contractility and mitochondrial function is central to cardiovascular disease. The progranulin gene () encodes glycoprotein PGRN (progranulin), a ubiquitous molecule with known anti-inflammatory property....
2.
Wu Y, Christodoulou A, Beumer J, Rigatti L, Fisher R, Ross M, et al.
Radiat Res
. 2024 Jul;
202(3):565-579.
PMID: 39074819
Victims of a radiation terrorist event will include pregnant women and unborn fetuses. Mitochondrial dysfunction and oxidative stress are key pathogenic factors of fetal radiation injury. The goal of this...
3.
Wu Y, Christodoulou A, Beumer J, Rigatti L, Fisher R, Ross M, et al.
bioRxiv
. 2024 Feb;
PMID: 38405696
One Sentence Summary: Mitochondrial-targeted gramicidin S (GS)-nitroxide JP4-039 is safe and effective radiation mitigator for mid-gestational fetal irradiation injury.
4.
Singh S, Bruder-Nascimento A, Costa R, Alves J, Bharathi S, Goetzman E, et al.
bioRxiv
. 2023 Nov;
PMID: 37961631
Objective: Cardiovascular disease (CVD) is a global health crisis and a leading cause of mortality. The intricate interplay between vascular contractility and mitochondrial function is central to CVD pathogenesis. The...
5.
Airik M, Arbore H, Childs E, Huynh A, Phua Y, Chen C, et al.
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107275
Karyomegalic interstitial nephritis (KIN) is a genetic adult-onset chronic kidney disease (CKD) characterized by genomic instability and mitotic abnormalities in the tubular epithelial cells. KIN is caused by recessive mutations...
6.
Dobrowolski S, Phua Y, Sudano C, Spridik K, Zinn P, Wang Y, et al.
Mol Genet Metab
. 2022 Apr;
136(1):38-45.
PMID: 35367142
Classical phenylketonuria (PKU, OMIM 261600) owes to hepatic deficiency of phenylalanine hydroxylase (PAH) that enzymatically converts phenylalanine (Phe) to tyrosine (Tyr). PKU neurologic phenotypes include impaired brain development, decreased myelination,...
7.
Sinsheimer A, Mohsen A, Bloom K, Karunanidhi A, Bharathi S, Wu Y, et al.
Mol Genet Metab
. 2021 Sep;
134(1-2):156-163.
PMID: 34556413
Acyl CoA Dehydrogenase 9 (ACAD9) is a member of the family of flavoenzymes that catalyze the dehydrogenation of acyl-CoAs to 2,3 enoyl-CoAs in mitochondrial fatty acid oxidation (FAO). Inborn errors...
8.
Dobrowolski S, Phua Y, Sudano C, Spridik K, Zinn P, Wang Y, et al.
Mol Genet Metab
. 2021 Apr;
PMID: 33846068
Classical phenylketonuria (PKU, OMIM 261600) owes to hepatic deficiency of phenylalanine hydroxylase (PAH) that enzymatically converts phenylalanine (Phe) to tyrosine (Tyr). PKU neurologic phenotypes include impaired brain development, decreased myelination,...
9.
Wang H, Lu J, Edmunds L, Kulkarni S, Dolezal J, Tao J, et al.
J Biol Chem
. 2016 Oct;
291(51):26241-26251.
PMID: 27738108
Hepatoblastoma (HB) is associated with aberrant activation of the β-catenin and Hippo/YAP signaling pathways. Overexpression of mutant β-catenin and YAP in mice induces HBs that express high levels of c-Myc...
10.
Otsubo C, Bharathi S, Uppala R, Ilkayeva O, Wang D, McHugh K, et al.
J Biol Chem
. 2015 Aug;
290(39):23897-904.
PMID: 26240137
The role of mitochondrial energy metabolism in maintaining lung function is not understood. We previously observed reduced lung function in mice lacking the fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase...