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Siti R Yusof

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Articles 15
Citations 2178
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Recent Articles
1.
Tan W, Samling B, Tong W, Chear N, Yusof S, Lim J, et al.
Polymers (Basel) . 2024 Feb; 16(4). PMID: 38399856
Since ancient times, essential oils (EOs) derived from aromatic plants have played a significant role in promoting human health. EOs are widely used in biomedical applications due to their medicinal...
2.
Chear N, Ching-Ga T, Khaw K, Leon F, Tan W, Yusof S, et al.
Metabolites . 2023 Mar; 13(3). PMID: 36984830
The genus is notable for its therapeutic potential in treating age-related dementia, such as Alzheimer's disease. A phytochemical study of the leaves of Malaysian Korth., afforded an undescribed natural corynanthe-type...
3.
Hanapi N, Chear N, Azizi J, Yusof S
Front Pharmacol . 2021 Dec; 12:751656. PMID: 34867362
Parallel to the growing use of kratom, there is a wealth of evidence from self-report, preclinical, and early clinical studies on therapeutic benefits of its alkaloids in particular for treating...
4.
Che Mohd Nassir C, Damodaran T, Yusof S, Norazit A, Chilla G, Huen I, et al.
Pharmaceutics . 2021 Aug; 13(8). PMID: 34452169
The distinctive anatomical assemble and functionally discrete multicellular cerebrovasculature dynamics confer varying rheological and blood-brain barrier permeabilities to preserve the integrity of cerebral white matter and its neural microenvironment. This...
5.
Hanapi N, Mohamad Arshad A, Abdullah J, Tengku Muhammad T, Yusof S
J Pharm Sci . 2020 Sep; 110(2):698-706. PMID: 32949562
Neurotherapeutic potentials of Centella asiatica and its reputation to boost memory, prevent cognitive deficits and improve brain functions are widely acknowledged. The plant's bioactive compounds, i.e. asiaticoside, madecassoside and asiatic...
6.
Tee H, Tan C, Yogarajah T, Lee M, Chai H, Hanapi N, et al.
PLoS Pathog . 2019 Nov; 15(11):e1007863. PMID: 31730673
Enterovirus A71 (EV-A71) causes hand, foot and mouth disease epidemics with neurological complications and fatalities. However, the neuropathogenesis of EV-A71 remains poorly understood. In mice, adaptation and virulence determinants have...
7.
Sekaran H, Gan C, A Latiff A, Harvey T, Mohd Nazri L, Hanapi N, et al.
Brain Res Bull . 2019 Jul; 152:63-73. PMID: 31301381
Cerebral hypoperfusion involved a reduction in cerebral blood flow, leading to neuronal dysfunction, microglial activation and white matter degeneration. The effects on the blood-brain barrier (BBB) however, have not been...
8.
Yusof S, Mohd Uzid M, Teh E, Hanapi N, Mohideen M, Mohamad Arshad A, et al.
Addict Biol . 2018 Aug; 24(5):935-945. PMID: 30088322
Mitragyna speciosa is reported to be beneficial for the management of chronic pain and opioid withdrawal in the evolving opioid epidemic. Data on the blood-brain barrier (BBB) transport of mitragynine...
9.
Nielsen S, Siupka P, Georgian A, Preston J, Toth A, Yusof S, et al.
J Vis Exp . 2017 Oct; (127). PMID: 28994773
The aim of this protocol presents an optimized procedure for the purification and cultivation of pBECs and to establish in vitro blood-brain barrier (BBB) models based on pBECs in mono-culture...
10.
Yusof S, Abbott N, Avdeef A
Eur J Pharm Sci . 2017 Jun; 106:274-286. PMID: 28614733
Most studies of blood-brain barrier (BBB) permeability and transport are conducted at a single pH, but more detailed information can be revealed by using multiple pH values. A pH-dependent biophysical...