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Nur Aziah Hanapi

Explore the profile of Nur Aziah Hanapi including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 73
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Recent Articles
1.
Lim P, Yap B, Tay Y, Hanapi N, Yusof S, Lee C
RSC Med Chem . 2024 Jun; 15(6):2179-2195. PMID: 38911152
Pharmacological inhibition of the SH2 domain-containing inositol 5-phosphatase 2 (SHIP2) by small-molecule compounds presents an attractive approach to modulate insulin sensitivity. Few drug-like SHIP2 inhibitors have been discovered to date....
2.
Hanapi N, Chear N, Azizi J, Yusof S
Front Pharmacol . 2021 Dec; 12:751656. PMID: 34867362
Parallel to the growing use of kratom, there is a wealth of evidence from self-report, preclinical, and early clinical studies on therapeutic benefits of its alkaloids in particular for treating...
3.
Hanapi N, Mohamad Arshad A, Abdullah J, Tengku Muhammad T, Yusof S
J Pharm Sci . 2020 Sep; 110(2):698-706. PMID: 32949562
Neurotherapeutic potentials of Centella asiatica and its reputation to boost memory, prevent cognitive deficits and improve brain functions are widely acknowledged. The plant's bioactive compounds, i.e. asiaticoside, madecassoside and asiatic...
4.
Tee H, Tan C, Yogarajah T, Lee M, Chai H, Hanapi N, et al.
PLoS Pathog . 2019 Nov; 15(11):e1007863. PMID: 31730673
Enterovirus A71 (EV-A71) causes hand, foot and mouth disease epidemics with neurological complications and fatalities. However, the neuropathogenesis of EV-A71 remains poorly understood. In mice, adaptation and virulence determinants have...
5.
Sekaran H, Gan C, A Latiff A, Harvey T, Mohd Nazri L, Hanapi N, et al.
Brain Res Bull . 2019 Jul; 152:63-73. PMID: 31301381
Cerebral hypoperfusion involved a reduction in cerebral blood flow, leading to neuronal dysfunction, microglial activation and white matter degeneration. The effects on the blood-brain barrier (BBB) however, have not been...
6.
Bhuvanendran S, Hanapi N, Ahemad N, Othman I, Yusof S, Shaikh M
Front Neurosci . 2019 Jun; 13:495. PMID: 31156375
Embelin is well-known in ethnomedicine and reported to have central nervous system activities. However, there is no report on blood-brain barrier (BBB) permeability of embelin. Here the BBB permeability of...
7.
Yusof S, Mohd Uzid M, Teh E, Hanapi N, Mohideen M, Mohamad Arshad A, et al.
Addict Biol . 2018 Aug; 24(5):935-945. PMID: 30088322
Mitragyna speciosa is reported to be beneficial for the management of chronic pain and opioid withdrawal in the evolving opioid epidemic. Data on the blood-brain barrier (BBB) transport of mitragynine...
8.
Liew K, Hanapi N, Chan K, Yusof S, Lee C
J Pharm Sci . 2016 Nov; 106(2):502-510. PMID: 27855959
Previously, several aurone derivatives were identified with promising neuroprotective activities. In developing these compounds to target the central nervous system (CNS), an assessment of their blood-brain barrier (BBB) permeability was...
9.
Ismail S, Hanapi N, Ab Halim M, Uchaipichat V, Mackenzie P
Molecules . 2010 Jul; 15(5):3578-92. PMID: 20657500
The effects of Andrographis paniculata and Orthosiphon stamineus extracts on the in vitro glucuronidation of 4-methylumbelliferone (4MU) by recombinant human UGTs, UGT1A1, UGT1A3, UGT1A6, UGT1A7, UGT1A8, UGT1A10, UGT2B7 and UGT2B15...