Sissy E Wamaitha
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Explore the profile of Sissy E Wamaitha including associated specialties, affiliations and a list of published articles.
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16
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788
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Recent Articles
1.
Wamaitha S, Rojas E, Monticolo F, Hsu F, Sosa E, Mackie A, et al.
bioRxiv
. 2025 Feb;
PMID: 39896577
The primate ovarian reserve is established during late fetal development and consists of quiescent primordial follicles in the ovarian cortex, each composed of granulosa cells surrounding an oocyte in dictate....
2.
Iyer D, Khoei H, van der Weijden V, Kagawa H, Pradhan S, Novatchkova M, et al.
Cell
. 2024 Sep;
187(23):6566-6583.e22.
PMID: 39332412
Many mammals can temporally uncouple conception from parturition by pacing down their development around the blastocyst stage. In mice, this dormant state is achieved by decreasing the activity of the...
3.
Lara M, Wamaitha S, Arabpour A, Hennebold J, Clark A, Sosa E
Stem Cell Res
. 2023 Nov;
73:103241.
PMID: 37976652
We generated and characterized a rhesus macaque induced pluripotent stem cell (iPSC) line using induced reprogramming of fibroblasts isolated from a rhesus macaque fetus. The fibroblasts were expanded and then...
4.
Wamaitha S, Nie X, Pandolfi E, Wang X, Yang Y, Stukenborg J, et al.
Dev Cell
. 2023 Aug;
58(20):2097-2111.e3.
PMID: 37582368
Formation of either an ovary or a testis during human embryonic life is one of the most important sex-specific events leading to the emergence of secondary sexual characteristics and sex...
5.
Lowe M, Yen M, Hsu F, Hosohama L, Hu Z, Chitiashvili T, et al.
Dev Cell
. 2022 Jun;
57(12):1482-1495.e5.
PMID: 35679863
Development of primordial germ cells (PGCs) is required for reproduction. During PGC development in mammals, major epigenetic remodeling occurs, which is hypothesized to establish an epigenetic landscape for sex-specific germ...
6.
Hancock G, Wamaitha S, Peretz L, Clark A
Development
. 2021 Mar;
148(6).
PMID: 33722957
The peri-implantation window of mammalian development is the crucial window for primordial germ cell (PGC) specification. Whereas pre-implantation dynamics are relatively conserved between species, the implantation window marks a stage...
7.
Gell J, Liu W, Sosa E, Chialastri A, Hancock G, Tao Y, et al.
Stem Cell Reports
. 2020 Feb;
14(3):433-446.
PMID: 32059791
The development of an in vitro system in which human primordial germ cell-like cells (hPGCLCs) are generated from human pluripotent stem cells (hPSCs) has been invaluable to further our understanding...
8.
Wamaitha S, Grybel K, Alanis-Lobato G, Gerri C, Ogushi S, McCarthy A, et al.
Nat Commun
. 2020 Feb;
11(1):764.
PMID: 32034154
Our understanding of the signalling pathways regulating early human development is limited, despite their fundamental biological importance. Here, we mine transcriptomics datasets to investigate signalling in the human embryo and...
9.
Wamaitha S, Niakan K
Curr Top Dev Biol
. 2018 Feb;
128:295-338.
PMID: 29477167
Understanding the progression of early human embryonic development prior to implantation is of fundamental biological importance. Greater insights into early developmental events may lead to clinical improvements, not only via...
10.
Fogarty N, McCarthy A, Snijders K, Powell B, Kubikova N, Blakeley P, et al.
Nature
. 2017 Oct;
551(7679):256.
PMID: 28976971
This corrects the article DOI: 10.1038/nature24033.