Sin Lam Tan
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Explore the profile of Sin Lam Tan including associated specialties, affiliations and a list of published articles.
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16
Citations
1223
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Recent Articles
1.
Chowdhary R, Zhang J, Tan S, Osborne D, Bajic V, Liu J
Int J Data Min Bioinform
. 2013 Jun;
7(4):450-62.
PMID: 23798227
Information on Protein Interactions (Pls) is valuable for biomedical research, but often lies buried in the scientific literature and cannot be readily retrieved. While much progress has been made over...
2.
Karnik S, Tan S, Berg B, Glurich I, Zhang J, Vidaillet H, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2013 Feb;
2012:5562-5.
PMID: 23367189
Electronic Health Records (EHR) contain large amounts of useful information that could potentially be used for building models for predicting onset of diseases. In this study, we have investigated the...
3.
Chowdhary R, Tan S, Zhang J, Karnik S, Bajic V, Liu J
PLoS One
. 2012 Apr;
7(4):e34480.
PMID: 22493694
Background: Protein interaction networks (PINs) specific within a particular context contain crucial information regarding many cellular biological processes. For example, PINs may include information on the type and directionality of...
4.
Chowdhary R, Tan S, Pavesi G, Jin J, Dong D, Mathur S, et al.
Am J Respir Cell Mol Biol
. 2012 Mar;
47(1):112-9.
PMID: 22383585
Many genes have been implicated in the pathogenesis of common respiratory and related diseases (RRDs), yet the underlying mechanisms are largely unknown. Differential gene expression patterns in diseased and healthy...
5.
Brahmachary M, Schonbach C, Yang L, Huang E, Tan S, Chowdhary R, et al.
BMC Bioinformatics
. 2007 Jan;
7 Suppl 5:S8.
PMID: 17254313
Background: Mammalian antimicrobial peptides (AMPs) are effectors of the innate immune response. A multitude of signals coming from pathways of mammalian pathogen/pattern recognition receptors and other proteins affect the expression...
6.
Tang S, Zhang Z, Tan S, Tang M, Kumar A, Ramadoss S, et al.
Nucleic Acids Res
. 2006 Nov;
35(Database issue):D732-6.
PMID: 17090589
Estrogen has a profound impact on human physiology affecting transcription of numerous genes. To decipher functional characteristics of estrogen responsive genes, we developed KnowledgeBase for Estrogen Responsive Genes (KBERG). Genes...
7.
Bajic V, Brent M, Brown R, Frankish A, Harrow J, Ohler U, et al.
Genome Biol
. 2006 Aug;
7 Suppl 1:S3.1-13.
PMID: 16925837
Background: This study analyzes the predictions of a number of promoter predictors on the ENCODE regions of the human genome as part of the ENCODE Genome Annotation Assessment Project (EGASP)....
8.
Bajic V, Tan S, Christoffels A, Schonbach C, Lipovich L, Yang L, et al.
PLoS Genet
. 2006 May;
2(4):e54.
PMID: 16683032
Using the two largest collections of Mus musculus and Homo sapiens transcription start sites (TSSs) determined based on CAGE tags, ditags, full-length cDNAs, and other transcript data, we describe the...
9.
Engstrom P, Suzuki H, Ninomiya N, Akalin A, Sessa L, Lavorgna G, et al.
PLoS Genet
. 2006 May;
2(4):e47.
PMID: 16683030
Mammalian genomes harbor a larger than expected number of complex loci, in which multiple genes are coupled by shared transcribed regions in antisense orientation and/or by bidirectional core promoters. To...
10.
Frith M, Wilming L, Forrest A, Kawaji H, Tan S, Wahlestedt C, et al.
PLoS Genet
. 2006 May;
2(4):e23.
PMID: 16683022
The mammalian transcriptome harbours shadowy entities that resist classification and analysis. In analogy with pseudogenes, we define pseudo-messenger RNA to be RNA molecules that resemble protein-coding mRNA, but cannot encode...