Simone Marcone
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Explore the profile of Simone Marcone including associated specialties, affiliations and a list of published articles.
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24
Citations
342
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Recent Articles
1.
Kane L, Mellotte G, Mylod E, Dowling P, Marcone S, Scaife C, et al.
Sci Rep
. 2025 Jan;
15(1):129.
PMID: 39747972
Integration of multi-omic data for the purposes of biomarker discovery can provide novel and robust panels across multiple biological compartments. Appropriate analytical methods are key to ensuring accurate and meaningful...
2.
Marcone S, Spadavecchia J, Khan M, Vella G, OConnell F, Pendino M, et al.
Cancers (Basel)
. 2024 Dec;
16(23).
PMID: 39682192
Methods: To overcome these limitations, pyrazinib was conjugated with gold nanoparticles (AuNP-P3), creating a novel formulation designed to enhance solubility, maintain bioactivity, and enable targeted delivery to tumour sites. Results:...
3.
Azam H, Veale C, Zitzmann K, Marcone S, Gallagher W, Prencipe M
PLoS One
. 2024 Dec;
19(12):e0309491.
PMID: 39671399
Background: The Androgen Receptor (AR) pathway is crucial in driving the progression of prostate cancer (PCa) to an advanced state. Despite the introduction of second-generation AR antagonists, such as enzalutamide,...
4.
Lynch S, Heeran A, Burke C, Lynam-Lennon N, Eustace A, Dean K, et al.
Cancers (Basel)
. 2024 Jun;
16(11).
PMID: 38893110
Advancements in oncology, especially with the era of precision oncology, is resulting in a paradigm shift in cancer care. Indeed, innovative technologies, such as artificial intelligence, are paving the way...
5.
Sundaramurthi H, Tonelotto V, Wynne K, OConnell F, OReilly E, Costa-Garcia M, et al.
Open Res Eur
. 2023 Nov;
3:88.
PMID: 37981907
Background: Uveal melanoma is a poor prognosis cancer. Ergolide, a sesquiterpene lactone isolated from , exerts anti-cancer properties. The objective of this study was to evaluate whether ergolide reduced metastatic...
6.
Lanas A, Tacconelli S, Contursi A, Piazuelo E, Bruno A, Ronci M, et al.
Cancers (Basel)
. 2023 May;
15(9).
PMID: 37173923
Background: The results of Aspirin prevention of colorectal adenomas in patients with familial adenomatous polyposis (FAP) are controversial. Methods: We conducted a biomarker-based clinical study in eight FAP patients treated...
7.
Contursi A, Fullone R, Szklanna-Koszalinska P, Marcone S, Lanuti P, Taus F, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672299
Background: Platelet-cancer cell interactions modulate tumor metastasis and thrombosis in cancer. Platelet-derived extracellular vesicles (EVs) can contribute to these outcomes. Methods: We characterized the medium-sized EVs (mEVs) released by thrombin-stimulated...
8.
ODowd D, OSullivan J, Marcone S
Cancers (Basel)
. 2022 Jul;
14(14).
PMID: 35884487
Oesophageal adenocarcinoma (OAC) incidence has increased dramatically in the developed world, yet outcomes remain poor. Extensive endoscopic surveillance programs among patients with Barrett's oesophagus (BO), the precursor lesion to OAC,...
9.
Uveal Melanoma Cell Line Proliferation Is Inhibited by Ricolinostat, a Histone Deacetylase Inhibitor
Sundaramurthi H, Garcia-Mulero S, Tonelotto V, Slater K, Marcone S, Piulats J, et al.
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35159049
Metastatic uveal melanoma (MUM) is characterized by poor patient survival. Unfortunately, current treatment options demonstrate limited benefits. In this study, we evaluate the efficacy of ACY-1215, a histone deacetylase inhibitor...
10.
Essa N, OConnell F, Prina-Mello A, OSullivan J, Marcone S
Cancer Lett
. 2021 Oct;
525:1-8.
PMID: 34662546
The epidemiological correlation between obesity and cancer is well characterized, but the biological mechanisms which regulate tumor development and response to therapy in obese cancer patients remain unclear. The tumor...