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Simone Hagmeyer

Explore the profile of Simone Hagmeyer including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 304
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Recent Articles
1.
Sauer A, Hagmeyer S, Grabrucker A
Int J Mol Sci . 2022 Jun; 23(11). PMID: 35682762
Epidemiological studies have shown a clear association between early life zinc deficiency and Autism Spectrum Disorders (ASD). In line with this, mouse models have revealed prenatal zinc deficiency as a...
2.
Daini E, Hagmeyer S, De Benedictis C, Cristovao J, Bodria M, Ross A, et al.
Transl Psychiatry . 2021 Nov; 11(1):562. PMID: 34741005
Autism Spectrum Disorders (ASD) are caused by a combination of genetic predisposition and nongenetic factors. Among the nongenetic factors, maternal immune system activation and zinc deficiency have been proposed. Intriguingly,...
3.
De Benedictis C, Haffke C, Hagmeyer S, Sauer A, Grabrucker A
Int J Mol Sci . 2021 Apr; 22(9). PMID: 33925953
In the last years, research has shown that zinc ions play an essential role in the physiology of brain function. Zinc acts as a potent neuromodulatory agent and signaling ions,...
4.
Pederzoli F, Ruozi B, Duskey J, Hagmeyer S, Sauer A, Grabrucker S, et al.
Pharmaceutics . 2019 Nov; 11(11). PMID: 31683907
The accumulation of amyloid β (Aβ) triggers a cascade of toxic events in Alzheimer's disease (AD). The KLVFF peptide can interfere with Aβ aggregation. However, the peptide suffers from poor...
5.
Hagmeyer S, Romao M, Cristovao J, Vilella A, Zoli M, Gomes C, et al.
Front Neurosci . 2019 Jul; 13:640. PMID: 31281238
Increasing evidence links proteins of the S100 family to the pathogenesis of Alzheimer's disease (AD). S100 proteins are EF-hand calcium-binding proteins with intra- and extracellular functions related to regulation of...
6.
Hagmeyer S, Sauer A, Grabrucker A
Front Synaptic Neurosci . 2018 Jun; 10:11. PMID: 29875651
The loss of one copy of SHANK3 (SH3 and multiple ankyrin repeat domains 3) in humans highly contributes to Phelan McDermid syndrome (PMDS). In addition, SHANK3 was identified as a...
7.
Hagmeyer S, Cristovao J, Mulvihill J, Boeckers T, Gomes C, Grabrucker A
Front Mol Neurosci . 2018 Feb; 10:456. PMID: 29386995
Neuronal metal ions such as zinc are essential for brain function. In particular synaptic processes are tightly related to metal and protein homeostasis, for example through extracellular metal-binding proteins. One...
8.
Vilella A, Belletti D, Sauer A, Hagmeyer S, Sarowar T, Masoni M, et al.
J Trace Elem Med Biol . 2018 Jan; 49:210-221. PMID: 29325805
A local dyshomeostasis of zinc ions in the vicinity of amyloid aggregates has been proposed in Alzheimer's disease (AD) due to the sequestration of zinc in senile plaques. While an...
9.
Sauer A, Pfaender S, Hagmeyer S, Tarana L, Mattes A, Briel F, et al.
Biometals . 2017 Jul; 30(5):643-661. PMID: 28717982
Zn is essential for growth and development. The bioavailability of Zn is affected by several factors such as other food components. It is therefore of interest, to understand uptake mechanisms...
10.
Pfaender S, Sauer A, Hagmeyer S, Mangus K, Linta L, Liebau S, et al.
Sci Rep . 2017 Mar; 7:45190. PMID: 28345660
Phelan McDermid Syndrome (PMDS) is a genetic disorder characterized by features of Autism spectrum disorders. Similar to reports of Zn deficiency in autistic children, we have previously reported high incidence...