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Andreas M Grabrucker

Explore the profile of Andreas M Grabrucker including associated specialties, affiliations and a list of published articles. Areas
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Articles 83
Citations 2120
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Recent Articles
1.
Blazewicz A, Wojnicka J, Grabrucker A, Sosnowski P, Trzpil A, Kozub-Pedrak A, et al.
Sci Rep . 2024 Nov; 14(1):29140. PMID: 39587337
The present preliminary study aimed to provide a targeted lipidomic analysis of Hashimoto (HT) and non-HT patients with well-controlled hypothyroidism as well as in healthy adults, and is the first...
2.
Blazewicz A, Kielbus M, Skorzynska-Dziduszko K, Grabrucker A, Jonklaas J, Sosnowski P, et al.
Molecules . 2024 Nov; 29(21). PMID: 39519809
Background: Hypothyroidism (HT) affects millions worldwide and can lead to various lipid disorders. The metabolic complexity and the influence of toxic elements in autoimmune and non-autoimmune HT subtypes are not...
3.
Abubaker M, Stanton J, Mahon O, Grabrucker A, Newport D, Mulvihill J
Mol Cell Biochem . 2024 Nov; PMID: 39499391
The pathological signature of Alzheimer's disease (AD) includes the accumulation of toxic protein aggregates, mainly consisting of amyloid beta (Aβ). Recent strides in fundamental research underscore the pivotal role of...
4.
Stanton J, Hans S, Zabetakis I, Grabrucker A
J Neurochem . 2024 Oct; 169(2):e16252. PMID: 39450676
Astrocytes are important regulators of neuronal development and activity. Their activation plays a key role in the response to many central nervous system (CNS) pathologies. However, reactive astrocytes are a...
5.
Hans S, Stanton J, Sauer A, Shiels K, Saha S, Lordan R, et al.
Lipids Health Dis . 2024 Apr; 23(1):113. PMID: 38643113
Background: Pro-inflammatory processes triggered by the accumulation of extracellular amyloid beta (Aβ) peptides are a well-described pathology in Alzheimer's disease (AD). Activated astrocytes surrounding Aβ plaques contribute to inflammation by...
6.
Coelho R, De Benedictis C, Sauer A, Figueira A, Faustino H, Grabrucker A, et al.
Int J Mol Sci . 2024 Feb; 25(3). PMID: 38339064
Proteinaceous aggregates accumulate in neurodegenerative diseases such as Alzheimer's Disease (AD), inducing cellular defense mechanisms and altering the redox status. S100 pro-inflammatory cytokines, particularly S100B, are activated during AD, but...
7.
Kury S, Stanton J, van Woerden G, Hsieh T, Rosenfelt C, Scott-Boyer M, et al.
medRxiv . 2024 Jan; PMID: 38293138
Neurodevelopmental proteasomopathies represent a distinctive category of neurodevelopmental disorders (NDD) characterized by genetic variations within the 26S proteasome, a protein complex governing eukaryotic cellular protein homeostasis. In our comprehensive study,...
8.
Dudzinska E, Grabrucker A, Kwiatkowski P, Sitarz R, Sienkiewicz M
Pharmaceuticals (Basel) . 2023 Oct; 16(10). PMID: 37895876
The visceral stimuli from the digestive tract are transmitted via afferent nerves through the spinal cord to the brain, where they are felt as pain. The overreaction observed in the...
9.
Philip R, Romeih E, Bailie E, Daly M, McGourty K, Grabrucker A, et al.
Breastfeed Med . 2023 Apr; 18(4):279-290. PMID: 37071630
Human milk (HM) fortification has been recommended for the nutritional optimization of very low-birthweight infants. This study analyzed the bioactive components of HM and evaluated fortification choices that could accentuate...
10.
Matuleviciene A, Siauryte K, Kuiper E, Grabrucker A
Eur J Med Genet . 2023 Apr; 66(6):104763. PMID: 37054968
Gastrointestinal (GI) problems are common in Phelan-McDermid syndrome (PMS). Chewing and swallowing difficulties, dental problems, reflux disease, cyclic vomiting, constipation, incontinence, diarrhoea, and nutritional deficiencies have been most frequently reported....