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Simona Ursu

Explore the profile of Simona Ursu including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 721
Followers 0
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Recent Articles
1.
Selvakumaran J, Ursu S, Bowerman M, Lu-Nguyen N, Wood M, Malerba A, et al.
Biomedicines . 2023 Oct; 11(10). PMID: 37893074
The blood-brain barrier (BBB) is the specialised microvasculature system that shields the central nervous system (CNS) from potentially toxic agents. Attempts to develop therapeutic agents targeting the CNS have been...
2.
Sumner E, Almeida B, Palman J, Bale P, Heard C, Holzinger D, et al.
Clin Rheumatol . 2022 Apr; 41(9):2825-2830. PMID: 35486225
The objective of this study was to determine the effectiveness of MRP8/14 as a predictor of disease flare in patients with juvenile idiopathic arthritis (JIA) following the withdrawal of methotrexate...
3.
Felgentreff K, Schuetz C, Baumann U, Klemann C, Viemann D, Ursu S, et al.
Front Immunol . 2021 Oct; 12:739675. PMID: 34594342
DNA damage occurs constantly in every cell triggered by endogenous processes of replication and metabolism, and external influences such as ionizing radiation and intercalating chemicals. Large sets of proteins are...
4.
Bongiovanni D, Klug M, Lazareva O, Weidlich S, Biasi M, Ursu S, et al.
Cell Death Dis . 2021 Jan; 12(1):50. PMID: 33414384
Novel coronavirus disease 2019 (COVID-19) is associated with a hypercoagulable state, characterized by abnormal coagulation parameters and by increased incidence of cardiovascular complications. With this study, we aimed to investigate...
5.
Cipolloni L, Baldari B, Besi L, Scopetti M, Di Sanzo M, Ursu S, et al.
J Forensic Leg Med . 2019 Jan; 62:19-24. PMID: 30634072
No abstract available.
6.
Gohar F, Anink J, Moncrieffe H, van Suijlekom-Smit L, Prince F, van Rossum M, et al.
J Rheumatol . 2018 Jan; 45(4):547-554. PMID: 29335345
Objective: Around one-third of patients with juvenile idiopathic arthritis (JIA) fail to respond to first-line methotrexate (MTX) or anti-tumor necrosis factor (TNF) therapy, with even fewer achieving ≥ American College...
7.
Anink J, van Suijlekom-Smit L, Otten M, Prince F, van Rossum M, Dolman K, et al.
Arthritis Res Ther . 2015 Aug; 17:200. PMID: 26249667
Introduction: Approximately 30% of juvenile idiopathic arthritis (JIA) patients fail to respond to anti-TNF treatment. When clinical remission is induced, some patients relapse after treatment has been stopped. We tested...
8.
Botta Gordon-Smith S, Ursu S, Eaton S, Moncrieffe H, Wedderburn L
Arthritis Rheumatol . 2014 Nov; 67(2):545-54. PMID: 25418634
Objective: To investigate the expression and adenosine-generating activity of the ecto-5'-nucleotidase CD73 on synovial fluid mononuclear cells (SFMCs) and peripheral blood mononuclear cells (PBMCs) from children with juvenile idiopathic arthritis...
9.
Bending D, Pesenacker A, Ursu S, Wu Q, Lom H, Thirugnanabalan B, et al.
J Immunol . 2014 Aug; 193(6):2699-708. PMID: 25092890
The maintenance of FOXP3 expression in CD25(hi) regulatory T cells (Tregs) is crucial to the control of inflammation and essential for successful Treg transfer therapies. Coexpression of CD25 and FOXP3...
10.
Moncrieffe H, Ursu S, Holzinger D, Patrick F, Kassoumeri L, Wade A, et al.
Rheumatology (Oxford) . 2013 Apr; 52(8):1467-76. PMID: 23620557
Objectives: In JIA there is an unmet need for biomarkers with which to identify patients who will respond well to MTX. The aim of this study was to define the...