Halima Moncrieffe
Overview
Explore the profile of Halima Moncrieffe including associated specialties, affiliations and a list of published articles.
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25
Citations
756
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Recent Articles
1.
Liu L, Khan A, Sanchez-Rodriguez E, Zanoni F, Li Y, Steers N, et al.
Nat Commun
. 2023 Feb;
14(1):655.
PMID: 36746961
No abstract available.
2.
Liu L, Khan A, Sanchez-Rodriguez E, Zanoni F, Li Y, Steers N, et al.
Nat Commun
. 2022 Nov;
13(1):6859.
PMID: 36369178
Immunoglobulin A (IgA) mediates mucosal responses to food antigens and the intestinal microbiome and is involved in susceptibility to mucosal pathogens, celiac disease, inflammatory bowel disease, and IgA nephropathy. We...
3.
Khan A, Shang N, Petukhova L, Zhang J, Shen Y, Hebbring S, et al.
J Am Soc Nephrol
. 2021 May;
32(8):2031-2047.
PMID: 33941608
Background: Genetic variants in complement genes have been associated with a wide range of human disease states, but well-powered genetic association studies of complement activation have not been performed in...
4.
Khodoun M, Chimote A, Ilyas F, Duncan H, Moncrieffe H, Kant K, et al.
Sci Adv
. 2020 Nov;
6(47).
PMID: 33208373
Lupus nephritis (LN) is an autoimmune disease with substantial morbidity/mortality and limited efficacy of available therapies. Memory T (Tm) lymphocytes infiltrate LN kidneys, contributing to organ damage. Analysis of LN,...
5.
Ramsey L, Moncrieffe H, Smith C, Sudman M, Marion M, Langefeld C, et al.
ACR Open Rheumatol
. 2019 Nov;
1(1):58-62.
PMID: 31777781
Objective: Variants in the gene, encoding a hepatic methotrexate (MTX) transporter, affect clearance of high-dose MTX. We tested whether in the *14 and *15 alleles of influenced the response to...
6.
Throm A, Moncrieffe H, Orandi A, Pingel J, Geurs T, Miller H, et al.
JCI Insight
. 2018 Aug;
3(15).
PMID: 30089725
Polyarticular juvenile idiopathic arthritis (JIA) is among the most challenging of the JIA subtypes to treat. Even with current biologic therapies, the disease remains difficult to control in a substantial...
7.
Ohl K, Nickel H, Moncrieffe H, Klemm P, Scheufen A, Foll D, et al.
Pediatr Rheumatol Online J
. 2018 Jun;
16(1):39.
PMID: 29925386
Background: Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)α...
8.
Gohar F, Anink J, Moncrieffe H, van Suijlekom-Smit L, Prince F, van Rossum M, et al.
J Rheumatol
. 2018 Jan;
45(4):547-554.
PMID: 29335345
Objective: Around one-third of patients with juvenile idiopathic arthritis (JIA) fail to respond to first-line methotrexate (MTX) or anti-tumor necrosis factor (TNF) therapy, with even fewer achieving ≥ American College...
9.
McIntosh L, Marion M, Sudman M, Comeau M, Becker M, Bohnsack J, et al.
Arthritis Rheumatol
. 2017 Jul;
69(11):2222-2232.
PMID: 28719732
Objective: Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and has a strong genomic component. To date, JIA genetic association studies have had limited sample sizes, used ...
10.
Moncrieffe H, Bennett M, Tsoras M, Luyrink L, Johnson A, Xu H, et al.
Rheumatology (Oxford)
. 2017 Jun;
56(9):1542-1551.
PMID: 28582527
Objective: The mechanisms that determine the efficacy or inefficacy of MTX in JIA are ill-defined. The objective of this study was to identify a gene expression transcriptional signature associated with...