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Simona Citro

Explore the profile of Simona Citro including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 243
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Recent Articles
1.
Medda A, Compagnoni M, Spini G, Citro S, Croci O, Campaner S, et al.
Cell Death Dis . 2023 Nov; 14(11):719. PMID: 37925449
Autophagy is important for the removal, degradation and recycling of damaged organelles, proteins, and lipids through the degradative action of lysosomes. In addition to its catabolic function, autophagy is important...
2.
Sabatini M, Compagnoni M, Maffini F, Miccolo C, Pagni F, Lombardi M, et al.
Front Mol Biosci . 2022 Aug; 9:940449. PMID: 36032664
Functional loss of E-cadherin is frequent during tumor progression and occurs through a variety of mechanisms, including proteolytic cleavage. E-cadherin downregulation leads to the conversion of a more malignant phenotype...
3.
Citro S, Miccolo C, Medda A, Ghiani L, Tagliabue M, Ansarin M, et al.
J Exp Clin Cancer Res . 2022 Feb; 41(1):59. PMID: 35144669
Background: Head and Neck cancer (HNC) is a fatal malignancy with poor prognosis. Human Papillomavirus (HPV) infection is becoming the prominent cause of HNC in the western world, and studying...
4.
Citro S, Bellini A, Medda A, Sabatini M, Tagliabue M, Chu F, et al.
Front Cell Infect Microbiol . 2020 Apr; 10:143. PMID: 32322564
P63, and in particular the most expressed ΔNp63α isoform, seems to have a critical role in the outcome of head and neck cancer. Many studies have been conducted to assess...
5.
Citro S, Bellini A, Miccolo C, Ghiani L, Carey T, Chiocca S
Br J Cancer . 2019 Feb; 120(6):658-667. PMID: 30765872
Background: Epidermal growth factor receptor (EGFR) overexpression is associated with the development of head and neck cancer (HNC) and represents one of the main therapeutic targets for this disease. The...
6.
Citro S, Chiocca S
Methods Mol Biol . 2016 Oct; 1510:329-337. PMID: 27761832
Attachment of ubiquitin or ubiquitin-like (Ubl) modifiers, such as the small ubiquitin-related modifier SUMO, is a posttranslational modification (PTM) that reversibly regulates the function and the stability of target proteins....
7.
Loponte S, Segre C, Senese S, Miccolo C, Santaguida S, Deflorian G, et al.
Sci Rep . 2016 Jul; 6:30213. PMID: 27458029
Histone deacetylases (HDACs) catalyze the removal of acetyl molecules from histone and non-histone substrates playing important roles in chromatin remodeling and control of gene expression. Class I HDAC1 is a...
8.
Citro S, Chiocca S
Methods Mol Biol . 2016 Jun; 1436:15-22. PMID: 27246205
Small ubiquitin-related modifier (SUMO) is an ubiquitin-like protein that is covalently attached to a variety of target proteins and has a significant role in their regulation. HDAC2 is an important...
9.
Lovisa S, Citro S, Sonego M, DallAcqua A, Ranzuglia V, Berton S, et al.
J Mol Cell Biol . 2015 Oct; 8(1):17-30. PMID: 26450989
Exposure of normal and tumor-derived cells to TGFβ results in different outcomes, depending on the regulation of key targets. The CDK inhibitor p27(Kip1) is one of these TGFβ targets and...
10.
Citro S, Miccolo C, Meloni L, Chiocca S
J Mol Cell Biol . 2015 Mar; 7(2):132-42. PMID: 25801958
Histone deacetylase 1 (HDAC1) is an important epigenetic controller involved in transcriptional regulation through modification of chromatin structure. Genetic and epigenetic changes and deregulation of signal transduction pathways have been...