Simona Chera
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Explore the profile of Simona Chera including associated specialties, affiliations and a list of published articles.
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52
Citations
1921
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Recent Articles
1.
Vasicek J, Kuznetsova K, Skiadopoulou D, Unger L, Chera S, Ghila L, et al.
Nat Methods
. 2024 Dec;
22(2):273-277.
PMID: 39653819
Amid the advances in genomics, the availability of large reference panels of human haplotypes is key to account for human diversity within and across populations. However, mass spectrometry-based proteomics does...
2.
Sinturel F, Chera S, Brulhart-Meynet M, Montoya J, Lefai E, Jornayvaz F, et al.
iScience
. 2024 Sep;
27(9):110820.
PMID: 39297163
Besides its beneficial effect on weight loss, gastric bypass surgery (GBS) may impact the circulating levels of phospho- and sphingolipids. However, long-term effects have not been explored. To investigate alterations...
3.
Mathisen A, Larsen U, Kavli N, Unger L, Daian L, Vacaru A, et al.
Commun Biol
. 2024 Jul;
7(1):833.
PMID: 38982170
Regeneration, the ability to replace injured tissues and organs, is a phenomenon commonly associated with lower vertebrates but is also observed in mammals, in specific tissues. In this study, we...
4.
Wang C, Abadpour S, Aizenshtadt A, Dalmao-Fernandez A, Hoyem M, Wilhelmsen I, et al.
Front Bioeng Biotechnol
. 2024 Jun;
12:1392575.
PMID: 38933536
Stem cell-derived islets (SC-islets) are not only an unlimited source for cell-based therapy of type 1 diabetes but have also emerged as an attractive material for modeling diabetes and conducting...
5.
Mathisen A, Vacaru A, Unger L, Lamba E, Mardare O, Daian L, et al.
Sci Rep
. 2024 Jun;
14(1):14669.
PMID: 38918575
Non-obese diabetes (NOD) mice are an established, spontaneous model of type 1 diabetes in which diabetes develops through insulitis. Using next-generation sequencing, coupled with pathway analysis, the molecular fingerprint of...
6.
Mathisen A, Legoy T, Larsen U, Unger L, Abadpour S, Paulo J, et al.
Mech Ageing Dev
. 2024 Jun;
220:111951.
PMID: 38825059
Animal longevity is a function of global vital organ functionality and, consequently, a complex polygenic trait. Yet, monogenic regulators controlling overall or organ-specific ageing exist, owing their conservation to their...
7.
Wang C, Abadpour S, Olsen P, Wang D, Stokowiec J, Chera S, et al.
Transpl Int
. 2024 Feb;
37:11900.
PMID: 38304198
The generation of insulin-producing cells from human-induced pluripotent stem cells holds great potential for diabetes modeling and treatment. However, existing protocols typically involve incubating cells with un-physiologically high concentrations of...
8.
Unger L, Mathisen A, Chera S, Legoy T, Ghila L
Int J Dev Biol
. 2024 Jan;
68(4):223-230.
PMID: 38270262
Differentiation of human induced pluripotent stem cells towards pancreatic islet endocrine cells is a complex process, involving the stepwise modulation of key developmental pathways, such as the Hedgehog signaling inhibition...
9.
Sinturel F, Chera S, Brulhart-Meynet M, Montoya J, Stenvers D, Bisschop P, et al.
Cell Rep Med
. 2023 Nov;
4(12):101299.
PMID: 38016481
Lipid homeostasis in humans follows a diurnal pattern in muscle and pancreatic islets, altered upon metabolic dysregulation. We employ tandem and liquid-chromatography mass spectrometry to investigate daily regulation of lipid...
10.
Mathisen A, Abadpour S, Legoy T, Paulo J, Ghila L, Scholz H, et al.
Acta Physiol (Oxf)
. 2023 Aug;
239(2):e14037.
PMID: 37621186
Aim: The variation in quality between the human islet samples represents a major problem for research, especially when used as control material. The assays assessing the quality of human islets...