Ismail Sebina
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Explore the profile of Ismail Sebina including associated specialties, affiliations and a list of published articles.
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32
Citations
665
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Recent Articles
1.
Sebina I, Bidgood C, Stalley F, Hartel G, Stark T, Callaway L, et al.
Sci Rep
. 2024 Dec;
14(1):30027.
PMID: 39627409
Mechanisms linking pre-pregnancy obesity to increased preterm birth risk are unclear. Here, we examined the impact of pre-pregnancy obesity on metabolites, Fms-related tyrosine kinase 3 ligand (Flt3L), and proinflammatory cytokine...
2.
Curren B, Ahmed T, Rashid R, Sebina I, Sikder M, Howard D, et al.
Cell Rep
. 2024 Nov;
43(11):114974.
PMID: 39535919
A poor maternal diet during pregnancy predisposes the infant to severe lower respiratory tract infections (sLRIs), which, in turn, increases childhood asthma risk; however, the underlying mechanisms remain poorly understood....
3.
Sebina I, Ngo S, Rashid R, Alorro M, Namubiru P, Howard D, et al.
Immunology
. 2024 Apr;
172(3):500-515.
PMID: 38584001
Lifestyle factors like poor maternal diet or antibiotic exposure disrupt early life microbiome assembly in infants, increasing the risk of severe lower respiratory infections (sLRI). Our prior studies in mice...
4.
Stylianou N, Sebina I, Matigian N, Monkman J, Doehler H, Rohl J, et al.
Clin Transl Immunology
. 2024 Feb;
13(2):e1488.
PMID: 38322491
Objectives: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus infection in pregnancy is associated with higher incidence of placental dysfunction, referred to by a few studies as a 'preeclampsia-like syndrome'....
5.
Agravat P, Loucaides E, Kumar M, Howells A, Molina Garcia A, Sebina I, et al.
Lancet Glob Health
. 2023 Oct;
11(11):e1794-e1804.
PMID: 37858589
Background: Worldwide, an estimated 4·4 million newborn deaths and stillbirths occurred in 2020, and 98% of these deaths occurred in low-income and middle-income countries (LMICs). We aimed to analyse new...
6.
Curren B, Ahmed T, Howard D, Ullah M, Sebina I, Rashid R, et al.
Mucosal Immunol
. 2023 Jul;
16(5):671-684.
PMID: 37506849
Rhinovirus-induced neutrophil extracellular traps (NETs) contribute to acute asthma exacerbations; however, the molecular factors that trigger NETosis in this context remain ill-defined. Here, we sought to implicate a role for...
7.
Sikder M, Rashid R, Ahmed T, Sebina I, Howard D, Ullah M, et al.
Immunity
. 2023 Apr;
56(5):1098-1114.e10.
PMID: 37003256
Poor maternal diet during pregnancy is a risk factor for severe lower respiratory infections (sLRIs) in the offspring, but the underlying mechanisms remain elusive. Here, we demonstrate that in mice...
8.
Sebina I, Rashid R, Sikder M, Rahman M, Ahmed T, Radford-Smith D, et al.
J Immunol
. 2022 Jun;
208(12):2806-2816.
PMID: 35675958
Infants with attenuated type III IFN (IFN-λ) responses are at increased risk of severe lower respiratory tract infection (sLRI). The IL-28Rα-chain and IL-10Rβ-chain form a heterodimeric receptor complex, necessary for...
9.
Manna S, McAuley J, Jacobson J, Nguyen C, Ullah M, Sebina I, et al.
mSphere
. 2022 Jan;
7(1):e0098421.
PMID: 35044807
Streptococcus pneumoniae (the pneumococcus) is a leading cause of pneumonia in children under 5 years of age. Coinfection by pneumococci and respiratory viruses enhances disease severity. Little is known about...
10.
Werder R, Ullah M, Rahman M, Simpson J, Lynch J, Collinson N, et al.
Am J Respir Crit Care Med
. 2021 Dec;
205(3):300-312.
PMID: 34860143
The alarmins IL-33 and HMGB1 (high mobility group box 1) contribute to type 2 inflammation and asthma pathogenesis. To determine whether P2Y-R (P2Y receptor), a purinergic GPCR (G protein-coupled receptor)...