Simon M Rushbrook
Overview
Explore the profile of Simon M Rushbrook including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
1083
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0
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Recent Articles
1.
Goode E, Fachal L, Panousis N, Moutsianas L, McIntyre R, Bai B, et al.
Nat Commun
. 2024 Nov;
15(1):9594.
PMID: 39505854
Genome-wide association studies of primary sclerosing cholangitis have identified 23 susceptibility loci. The majority of these loci reside in non-coding regions of the genome and are thought to exert their...
2.
Moreno-Gonzalez M, Hampton K, Ruiz P, Beasy G, Nagies F, Parker A, et al.
JHEP Rep
. 2024 Sep;
6(10):101159.
PMID: 39314550
Background & Aims: Senescence has been reported to have differential functions in cholangiocytes and hepatic stellate cells (HSCs) during human and murine cholestatic disease, being detrimental in biliary cells and...
3.
Khan S, Rushbrook S, Kendall T, Zen Y, Albazaz R, Manoharan P, et al.
Gut
. 2024 Aug;
74(3):504-505.
PMID: 39160057
No abstract available.
4.
Rushbrook S, Kendall T, Zen Y, Albazaz R, Manoharan P, Pereira S, et al.
Gut
. 2023 Sep;
73(1):16-46.
PMID: 37770126
These guidelines for the diagnosis and management of cholangiocarcinoma (CCA) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included a multidisciplinary team of experts...
5.
Mulcahy V, Liaskou E, Martin J, Kotagiri P, Badrock J, Jones R, et al.
Hepatol Commun
. 2023 Apr;
7(4).
PMID: 37026715
Background Aims: In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid-the UDCA response-accurately predicts long-term outcome. Molecular characterization of patients stratified by...
6.
Han Y, Byun J, Zhu C, Sun R, Roh J, Cordell H, et al.
Nat Commun
. 2023 Feb;
14(1):1069.
PMID: 36828809
Primary sclerosing cholangitis (PSC) is a rare autoimmune bile duct disease that is strongly associated with immune-mediated disorders. In this study, we implemented multitrait joint analyses to genome-wide association summary...
7.
Thomas J, Modos D, Rushbrook S, Powell N, Korcsmaros T
Front Immunol
. 2022 Feb;
13:829525.
PMID: 35185922
Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of the gastrointestinal tract that arises due to complex interactions between host genetic risk factors, environmental factors, and a dysbiotic...
8.
Isaacs-Ten A, Echeandia M, Moreno-Gonzalez M, Brion A, Goldson A, Philo M, et al.
Hepatology
. 2020 Mar;
72(6):2090-2108.
PMID: 32168395
Background And Aims: Mounting evidence supports an association between cholestatic liver disease and changes in the composition of the microbiome. Still, the role of the microbiome in the pathogenesis of...
9.
Goode E, Hirschfield G, Rushbrook S
Hepatology
. 2019 Sep;
71(1):399-400.
PMID: 31550385
No abstract available.
10.
Chapman M, Thorburn D, Hirschfield G, Webster G, Rushbrook S, Alexander G, et al.
Gut
. 2019 Jun;
68(8):1356-1378.
PMID: 31154395
These guidelines on the management of primary sclerosing cholangitis (PSC) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included medical representatives from hepatology and...