Simon M Rushbrook
Overview
Explore the profile of Simon M Rushbrook including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
1083
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0
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Recent Articles
11.
Gurusamy K, Walmsley M, Davidson B, Frier C, Fuller B, Madden A, et al.
BMJ Open
. 2019 Mar;
9(3):e025045.
PMID: 30850408
Objectives: There is a mismatch between research questions considered important by patients, carers and healthcare professionals and the research performed in many fields of medicine. The non-alcohol-related liver and gallbladder...
12.
Goode E, Clark A, Mells G, Srivastava B, Spiess K, Gelson W, et al.
Hepatology
. 2018 Dec;
69(5):2120-2135.
PMID: 30566748
We sought to identify factors that are predictive of liver transplantation or death in patients with primary sclerosing cholangitis (PSC), and to develop and validate a contemporaneous risk score for...
13.
Fine-Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease
Blokker B, Maijo M, Echeandia M, Galduroz M, Patterson A, Ten A, et al.
Hepatology
. 2018 Sep;
69(2):699-716.
PMID: 30229970
Cholestasis comprises aetiologically heterogeneous conditions characterized by accumulation of bile acids in the liver that actively contribute to liver damage. Sirtuin 1 (SIRT1) regulates liver regeneration and bile acid metabolism...
14.
Alberts R, de Vries E, Goode E, Jiang X, Sampaziotis F, Rombouts K, et al.
Gut
. 2017 Aug;
67(8):1517-1524.
PMID: 28779025
Objective: Primary sclerosing cholangitis (PSC) is a genetically complex, inflammatory bile duct disease of largely unknown aetiology often leading to liver transplantation or death. Little is known about the genetic...
15.
Ji S, Juran B, Mucha S, Folseraas T, Jostins L, Melum E, et al.
Nat Genet
. 2016 Dec;
49(2):269-273.
PMID: 27992413
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct destruction; ∼75% of patients have comorbid inflammatory bowel disease (IBD). We undertook the largest genome-wide association study...
16.
Kok K, Wharton R, Rushbrook S
Gastroenterology
. 2016 May;
150(7):e5-e6.
PMID: 27143591
No abstract available.
17.
Goode E, Rushbrook S
Ther Adv Chronic Dis
. 2016 Jan;
7(1):68-85.
PMID: 26770670
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that progresses to end-stage liver disease and cirrhosis. Recurrent biliary inflammation is thought to lead to dysplasia, and as such...
18.
Kwok C, Krupa L, Mahtani A, Kaye D, Rushbrook S, Phillips M, et al.
Biomed Res Int
. 2013 Nov;
2013:295153.
PMID: 24222902
Background: Studies have suggested that albumin has a value in cirrhotic patients undergoing paracentesis but its value in infection and sepsis is less clear. We planned to perform a meta-analysis...
19.
Brooks J, Gelson W, Rushbrook S
Ther Adv Chronic Dis
. 2013 Jul;
4(4):157-66.
PMID: 23819019
Hepatitis B virus (HBV) is a small nonenveloped DNA virus that is a member of the Hepadnaviridae family. Chronic HBV infection is estimated to effect more than 350 million people...
20.
Goode E, Simpson B, Rushbrook S
Gastroenterology
. 2013 Apr;
144(7):e14-5.
PMID: 23623881
No abstract available.