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Simon Lindner

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Articles 98
Citations 959
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Recent Articles
1.
Dinkel L, Hummel S, Zenatti V, Malara M, Tillmann Y, Colombo A, et al.
Sci Transl Med . 2024 Dec; 16(776):eadl4616. PMID: 39630885
Niemann-Pick type C (NPC) disease is an inherited lysosomal storage disorder mainly driven by mutations in the gene, causing lipid accumulation within late endosomes/lysosomes and resulting in progressive neurodegeneration. Although...
2.
Shojaei M, Schaefer R, Schlepckow K, Kunze L, Struebing F, Brunner B, et al.
Theranostics . 2024 Oct; 14(16):6319-6336. PMID: 39431020
Triggering receptor expressed on myeloid cells 2 (TREM2) plays an essential role in microglia activation and is being investigated as a potential therapeutic target for modulation of microglia in several...
3.
Kunte S, Wenter V, Toms J, Lindner S, Unterrainer M, Eilsberger F, et al.
Eur J Nucl Med Mol Imaging . 2024 Oct; 52(3):900-912. PMID: 39404789
Purpose: The novel F-labeled somatostatin receptor (SSTR)-directed radiotracer [F]SiTATE demonstrated promising results for the imaging of various SSTR-expressing tumor types. Although thyroid carcinomas (TC) express SSTR, data on [F]SiTATE PET/CT...
4.
Lindheimer F, Lindner M, Oos R, Honarpisheh M, Zhang Y, Lei Y, et al.
Front Nucl Med . 2024 Oct; 3:1157480. PMID: 39355020
Introduction: Islet xenotransplantation may be a therapeutic option in type 1 diabetes. Recent advances in generating genetically modified source pigs offer advantages as immune suppressants can potentially be eliminated after...
5.
Kunte S, Unterrainer L, Kunz W, Winkelmann M, Lindner S, Jurkschat K, et al.
Clin Nucl Med . 2024 Oct; 49(12):e689-e690. PMID: 39354685
A 64-year-old woman with meningioma presented with left-sided lenticulostriatal ischemia following craniotomy and debulking of a sphenoid wing meningioma. For subsequent radiotherapy planning, an SSTR-targeted PET/CT using the novel ligand...
6.
Zatcepin A, Gnorich J, Rauchmann B, Bartos L, Wagner S, Franzmeier N, et al.
Mol Neurodegener . 2024 Sep; 19(1):64. PMID: 39238030
Background: Microglial activation is one hallmark of Alzheimer disease (AD) neuropathology but the impact of the regional interplay of microglia cells in the brain is poorly understood. We hypothesized that...
7.
Britsch S, Britsch M, Hahn L, Langer H, Lindner S, Akin I, et al.
Heart Lung . 2024 Jun; 68:52-59. PMID: 38924856
Background: Cardiogenic shock (CS) is characterized by high mortality and requires accurate prognostic tools to predict outcomes and guide treatment. The Society for Cardiovascular Angiography and Interventions (SCAI) shock classification...
8.
Lindner S, Hoermann C, Teichert J, Ziyadova S, Michels-Zetsche J, Neetz B, et al.
BMC Pulm Med . 2024 Jun; 24(1):289. PMID: 38902702
Introduction: The diaphragm thickening fraction (DTF) may be a valuable tool for estimating respiratory effort in non-invasive ventilation. The primary aim of this physiological study is the investigation of the...
9.
Lakatos B, Ladanyi Z, Fabian A, Ehrenberger R, Turschl T, Bagyura Z, et al.
Front Cardiovasc Med . 2024 Jun; 11:1399874. PMID: 38863897
Introduction And Aims: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is an increasingly utilized therapeutic choice in patients with cardiogenic shock, however, high complication rate often counteracts with its beneficial cardiopulmonary effects....
10.
Shojaei M, Zhou Q, Palumbo G, Schaefer R, Kaskinoro J, Vehmaan-Kreula P, et al.
ACS Pharmacol Transl Sci . 2024 May; 7(5):1404-1414. PMID: 38751620
Aggregating poly(glycine-alanine) (poly-GA) is derived from the unconventional translation of the pathogenic intronic hexanucleotide repeat expansion in the gene, which is the most common genetic cause of frontotemporal dementia (FTD)...