Simon Leclerc
Overview
Explore the profile of Simon Leclerc including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
111
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0
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Recent Articles
1.
Pouliot L, Desy L, Lemieux S, Celis-Preciado C, Lemaire-Paquette S, Duval M, et al.
ERJ Open Res
. 2025 Feb;
11(1).
PMID: 40008174
https://bit.ly/4dxP7Pd.
2.
Celis-Preciado C, Leclerc S, Duval M, Cliche D, Brazeau L, Vezina F, et al.
Eur Respir J
. 2025 Feb;
PMID: 39947666
Background: Asthma attacks are heterogeneous. It is not known whether the response to oral corticosteroids (OCS) in acute asthma varies according to type-2 (T2) inflammatory biomarkers, blood eosinophil count (BEC)...
3.
Tervonen A, Leclerc S, Ruokolainen V, Tieu K, Lyonnais S, Niskanen H, et al.
bioRxiv
. 2025 Jan;
PMID: 39803437
Mechanical properties of the nucleus are remodeled not only by extracellular forces transmitted to the nucleus but also by internal modifications, such as those induced by viral infections. During herpes...
4.
5.
Kunnas K, Vihinen-Ranta M, Leclerc S
MicroPubl Biol
. 2024 Sep;
2024.
PMID: 39228992
During infection, Herpes simplex virus type 1 (HSV-1) alters the mitochondrial structure and function of the host cell. Live-cell imaging with fluorescent reporters revealed increased mitochondrial calcium and a transient...
6.
Alsalemi N, Sadowski C, Elftouh N, Kilpatrick K, Houle S, Leclerc S, et al.
BMJ Health Care Inform
. 2024 Aug;
31(1).
PMID: 39209331
Background: Older patients with diabetic kidney disease (DKD) often do not receive optimal pharmacological treatment. Current clinical practice guidelines (CPGs) do not incorporate the concept of personalised care. Clinical decision...
7.
Leclerc S, Gupta A, Ruokolainen V, Chen J, Kunnas K, Ekman A, et al.
PLoS Pathog
. 2024 Apr;
20(4):e1011829.
PMID: 38620036
Viruses target mitochondria to promote their replication, and infection-induced stress during the progression of infection leads to the regulation of antiviral defenses and mitochondrial metabolism which are opposed by counteracting...
8.
Celis-Preciado C, Leclerc S, Duval M, Cliche D, Larivee P, Lemaire-Paquette S, et al.
BMJ Open Respir Res
. 2023 Nov;
10(1).
PMID: 37940357
Introduction: Asthma and its associated exacerbation are heterogeneous. Although severe asthma attacks are systematically prescribed corticosteroids and often antibiotics, little is known about the variability of response to these therapies....
9.
Mattola S, Mantyla E, Aho V, Salminen S, Leclerc S, Oittinen M, et al.
Front Cell Dev Biol
. 2022 Dec;
10:1070599.
PMID: 36568985
The nuclear export factor CRM1-mediated pathway is known to be important for the nuclear egress of progeny parvovirus capsids in the host cells with virus-mediated cell cycle arrest at G2/M....
10.
Beaubien-Souligny W, Leclerc S, Verdin N, Ramzanali R, Fox D
Can J Kidney Health Dis
. 2022 Oct;
9:20543581221127940.
PMID: 36246342
Purpose Of Review: Diabetes affects almost a 10th of the Canadian population, and diabetic nephropathy is one of its main complications. It remains a leading cause of kidney failure despite...