Simon Leclerc
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Explore the profile of Simon Leclerc including associated specialties, affiliations and a list of published articles.
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21
Citations
111
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Recent Articles
11.
Hada I, Shimizu A, Takematsu H, Nishibori Y, Kimura T, Fukutomi T, et al.
J Am Soc Nephrol
. 2022 Aug;
33(11):2008-2025.
PMID: 35985815
Background: The cause of podocyte injury in idiopathic nephrotic syndrome (INS) remains unknown. Although recent evidence points to the role of B cells and autoimmunity, the lack of animal models...
12.
Leclerc S, Benkirane K, Nadeau-Fredette A, Elftouh N, Lafrance J, Pichette V, et al.
Can J Kidney Health Dis
. 2021 Nov;
8:20543581211052729.
PMID: 34721885
Background: Quantification of the M-type phospholipase A2 receptor antibodies (anti-PLA2R) is now an essential tool for diagnosis and management of primary membranous nephropathy (MN). Since October 2018, Hôpital Maisonneuve-Rosemont (HMR)...
13.
Leclerc S, Lamarche C
Curr Opin Nephrol Hypertens
. 2021 Aug;
30(6):584-592.
PMID: 34412086
Purpose Of Review: Current immunosuppressive regimens used in kidney transplantation are sometimes ineffective and carry significant risks of morbidity and mortality. Cellular therapies are a promising alternative to prolong graft...
14.
Leclerc S, Royal V, Lamarche C, Laurin L
Am J Kidney Dis
. 2021 Jul;
78(4):607-610.
PMID: 34242687
We report a case of minimal change disease (MCD) with severe acute kidney injury (AKI) following the first injection of the ChAdOx1 nCoV-19 (AZD1222) vaccine from Oxford-AstraZeneca against coronavirus disease...
15.
Leclerc S, Kitagawa K
Front Mol Biosci
. 2021 Apr;
8:642732.
PMID: 33869284
Chromosome instability is a hallmark of cancer and is caused by inaccurate segregation of chromosomes. One cellular structure used to avoid this fate is the kinetochore, which binds to the...
16.
Leclerc S, Royal V, Dufresne S, Mondesert B, Laurin L
Kidney Int Rep
. 2020 Dec;
5(12):2393-2398.
PMID: 33305139
No abstract available.
17.
Leclerc S, Nadeau-Fredette A, Elftouh N, Lafrance J, Pichette V, Laurin L
Kidney Int Rep
. 2020 Aug;
5(8):1180-1187.
PMID: 32775817
Introduction: To prevent bleeding after native kidney biopsy (NKB), nephrologists often prescribe desmopressin, especially for patients with reduced estimated glomerular filtration rate (eGFR) at risk of uremia-related platelet dysfunction. However,...
18.
BHi-Cect: a top-down algorithm for identifying the multi-scale hierarchical structure of chromosomes
Kumar V, Leclerc S, Taniguchi Y
Nucleic Acids Res
. 2020 Feb;
48(5):e26.
PMID: 32009153
High-throughput chromosome conformation capture (Hi-C) technology enables the investigation of genome-wide interactions among chromosome loci. Current algorithms focus on topologically associating domains (TADs), that are contiguous clusters along the genome...
19.
Leclerc S, Laurin L, Lafrance J, Lamarche C, Ouimet D, Paquette F, et al.
Int J Clin Pharmacol Ther
. 2019 Oct;
57(12):603-606.
PMID: 31657712
Residual renal function and diuresis preservation are associated with improved volume control and lower mortality in peritoneal dialysis (PD). Loop diuretics are used to maintain diuresis, although their optimal dosage...
20.
Leclerc S, Arntz Y, Taniguchi Y
J Vis Exp
. 2019 May;
(146).
PMID: 31058902
Cell proteomes are often characterized using electrophoresis assays, where all species of proteins in the cells are non-specifically labeled with a fluorescent dye and are spotted by a photodetector following...